Evidence map›Paper›PMID 31483820›Full record

ArticlePloS one2019

High-degree centrum semiovale-perivascular spaces are associated with development of subdural fluid in mild traumatic brain injury.

Hae-Won Koo, Minkyung Oh, Hyung Koo Kang, Yung Ki Park, Byung-Jou Lee, Seong Rok Han, Sang Won Yoon, Chan Young Choi, Moon-Jun Sohn, Chae Heuck Lee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hae-Won KooDepartment of Neurosurgery, Ilsan Paik Hospital, College of Medicine, Inje University, Neuroscience, Radiosurgery and Adaptive Hybrid Neurosurgery Research Center, Goyang, Korea.ORCID 0000-0001-7014-3005
Minkyung OhDepartment of Pharmacology, College of Medicine and Clinical Trial Center, Busan Paik Hospital, Inje University, Busan, Korea.
Hyung Koo KangDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ilsan Paik Hospital, College of Medicine, Inje University, Goyang, Korea.
Yung Ki ParkDepartment of Neurosurgery, Ilsan Paik Hospital, College of Medicine, Inje University, Neuroscience, Radiosurgery and Adaptive Hybrid Neurosurgery Research Center, Goyang, Korea.
Byung-Jou LeeDepartment of Neurosurgery, Ilsan Paik Hospital, College of Medicine, Inje University, Neuroscience, Radiosurgery and Adaptive Hybrid Neurosurgery Research Center, Goyang, Korea.
Seong Rok HanDepartment of Neurosurgery, Ilsan Paik Hospital, College of Medicine, Inje University, Neuroscience, Radiosurgery and Adaptive Hybrid Neurosurgery Research Center, Goyang, Korea.
Sang Won YoonDepartment of Neurosurgery, Ilsan Paik Hospital, College of Medicine, Inje University, Neuroscience, Radiosurgery and Adaptive Hybrid Neurosurgery Research Center, Goyang, Korea.
Chan Young ChoiDepartment of Neurosurgery, Ilsan Paik Hospital, College of Medicine, Inje University, Neuroscience, Radiosurgery and Adaptive Hybrid Neurosurgery Research Center, Goyang, Korea.
Moon-Jun SohnDepartment of Neurosurgery, Ilsan Paik Hospital, College of Medicine, Inje University, Neuroscience, Radiosurgery and Adaptive Hybrid Neurosurgery Research Center, Goyang, Korea.
Chae Heuck LeeDepartment of Neurosurgery, Ilsan Paik Hospital, College of Medicine, Inje University, Neuroscience, Radiosurgery and Adaptive Hybrid Neurosurgery Research Center, Goyang, Korea.
Inje University Ilsan Paik Hospital · KRInje University Busan Paik Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere centrum semiovale perivascular spaces (CSO-PVSs) are associated with the onset of brain atrophy and dementia. This study explored the relationship between severity of CSO-PVS and development of subdural fluid (SDF) in patients with mild traumatic brain injury (TBI), with the aim of investigating independent radiological risk factors for development of SDF.

methodsThe study cohort comprised 222 patients with a mean age of 51 years (64.0% men) who presented with mild TBI from January 2013 to November 2016. In this study, mild TBI was defined as a Glasgow Coma Scale (GCS) of ≥ 13, Post-Traumatic Amnesia (PTA) of <1 day, and Loss of Consciousness (LOC) of <30 minutes. The severity of CSO-PVS was categorized as low or high-degree.

resultsAmong the 222 enrolled patients, 38 (17.1%) and 90 (40.5%) had high-degree PVS in the basal ganglia (BG) and centrum semiovale, respectively. Compared with patients who did not develop SDF, the mean age of patients who developed SDF was significantly higher (47.41 years versus 60.33 years, P < 0.0001). The incidence of de novo SDF was significantly higher in men than in women (77.8% versus 59.5%, P = 0.0151). Patients who showed SDF on brain computed tomography at admission more frequently developed de novo SDF (68.5% versus 38.1%, P < 0.0001). In multivariate logistic regression analysis of risk factors, high-degree CSO-PVS, male sex, initial SDF on admission, and old age were independently associated with development of de novo SDF after mild TBI. In Cox proportional hazards models of risk factors for SDF-development free survival rate, high-degree CSO-PVS, old age, and initial subdural hemorrhage showed statistically significant differences.

conclusionsOur study might help neurosurgeons determine the frequency of brain CT or the duration of follow-up for patients who present with mild TBI with high-degree CSO-PVS.

Indexed as

Brain Injuries, TraumaticCohort StudiesFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesRisk FactorsTomography, X-Ray ComputedWhite Matter

Identifiers

PMID31483820
PMCPMC6726225
OpenAlexW2971655127

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.