Evidence map›Paper›PMID 31483610›Full record

ArticleBioconjugate chemistry2019

β-Hydroxy-Stabilized Boron-Nitrogen Heterocycles Enable Rapid and Efficient C-Terminal Protein Modification.

Han Gu, Saptarshi Ghosh, Richard J Staples, Susan L Bane

Abstract read
In one paragraph

Article in Bioconjugate chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Iminoboronates as Dual-Purpose Linkers in Chemical Probe Development.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Han GuDepartment of Chemistry , Binghamton University, State University of New York , Binghamton , New York 13902 , United States.
Saptarshi GhoshDepartment of Chemistry , Binghamton University, State University of New York , Binghamton , New York 13902 , United States.
Richard J StaplesDepartment of Chemistry and Chemical Biology , Michigan State University , East Lansing , Michigan 48824 , United States.ORCID 0000-0003-2760-769X
Susan L BaneDepartment of Chemistry , Binghamton University, State University of New York , Binghamton , New York 13902 , United States.ORCID 0000-0002-4270-6314

Funding

Coupling Through Boron: Fast, Tunable and Versatile Bioorthogonal Reactions Producing Boron-Containing HeterocyclesR15CA227747 · NCI · STATE UNIVERSITY OF NY,BINGHAMTON · PI BANE, SUSAN L · 2018 to 2018
$447k
NCI NIH HHS R15 CA227747
6 · The paper itself

Abstract

Bioorthogonal chemistry has enabled the development of bioconjugates in physiological environments while averting interference from endogenous biomolecules. Reactions between carbonyl-containing molecules and alkoxyamines or hydrazines have experienced a resurgence in popularity in bioorthogonal chemistry owing to advances that allow the reactions to occur under physiological conditions. In particular,

Indexed as

BoronHeterocyclic CompoundsKineticsModels, MolecularNitrogenProtein ConformationProteinsBoronHeterocyclic CompoundsNitrogenProteins

Identifiers

PMID31483610
PMCPMC7354006

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.