Evidence map›Paper›PMID 31483474›Full record

ArticleJAMA network open2019

Quality of Chronic Kidney Disease Management in Canadian Primary Care.

Aminu K Bello, Paul E Ronksley, Navdeep Tangri, Julia Kurzawa, Mohamed A Osman, Alexander Singer, Allan K Grill, Dorothea Nitsch, John A Queenan, James Wick and 7 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JAMA network open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03365063 (Integrating Risk-based Care for Patients With Chronic Kidney Disease), which is not on this map. Cited by 59 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 3 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03365063 naterminatednot on this map

Integrating Risk-based Care for Patients With Chronic Kidney Disease (CKD) in the Community

TypeinterventionalSponsorUniversity of ManitobaRan2018 to 2020Enrolled5,600ConditionsChronic Kidney DiseaseArmsActive Knowledge Translation
3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 3 syntheses or guidelines pooled it, 98 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Inappropriate use of clinical practices in Canada: a systematic review.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022
    Pooled it
  4. Article
  5. Article
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  7. Care Processes and Clinical Responses to Newly Detected Albuminuria: The Stockholm Creatinine Measurements (SCREAM) Project.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 3 countries.

Aminu K BelloDivision of Nephrology and Immunology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Paul E RonksleyDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Navdeep TangriDepartment of Medicine, Max Rady College of Medicine, Winnipeg, Manitoba, Canada.
Julia KurzawaDivision of Nephrology and Immunology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Mohamed A OsmanDivision of Nephrology and Immunology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Alexander SingerDepartment of Family Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Allan K GrillDepartment of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada.
Dorothea NitschDepartment of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
John A QueenanCanadian Primary Care Sentinel Surveillance Network, Department of Family Medicine, Queen's University, Kingston, Ontario, Canada.
James WickDepartment of Medicine, University of Calgary, Calgary, Alberta, Canada.
Cliff LindemanDepartment of Family Medicine, University of Alberta, Edmonton, Alberta, Canada.
Boglarka SoosDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Delphine S TuotDivision of Nephrology, University of California, San Francisco.
Soroush ShojaiDivision of Nephrology and Immunology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
K Scott BrimbleDivision of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Dee ManginDepartment of Family Medicine, McMaster University, Hamilton, Ontario, Canada.
Neil DrummondDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
University of Alberta · CAUniversity of Calgary · CAMcMaster University · CAUniversity of Manitoba · CALondon School of Hygiene & Tropical Medicine · GBQueen's University · CAUniversity of California, San Francisco · USUniversity of Toronto · CA

Funding

CIHR RN281786
6 · The paper itself

Abstract

Importance: Although patients with chronic kidney disease (CKD) are routinely managed in primary care settings, no nationally representative study has assessed the quality of care received by these patients in Canada. Objective: To evaluate the current state of CKD management in Canadian primary care practices to identify care gaps to guide development and implementation of national quality improvement initiatives. Design, Setting, and Participants: This cross-sectional study leveraged Canadian Primary Care Sentinel Surveillance Network data from January 1, 2010, to December 31, 2015, to develop a cohort of 46 162 patients with CKD managed in primary care practices. Data analysis was performed from August 8, 2018, to July 31, 2019. Main Outcomes and Measures: The study examined the proportion of patients with CKD who met a set of 12 quality indicators in 6 domains: (1) detection and recognition of CKD, (2) testing and monitoring of kidney function, (3) use of recommended medications, (4) monitoring after initiation of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs), (5) management of blood pressure, and (6) monitoring for glycemic control in those with diabetes and CKD. The study also analyzed associations of divergence from these quality indicators. Results: The cohort comprised 46 162 patients (mean [SD] age, 69.2 [14.0] years; 25 855 [56.0%] female) with stage 3 to 5 CKD. Only 4 of 12 quality indicators were met by 75% or more of the study cohort. These indicators were receipt of an outpatient serum creatinine test within 18 months after confirmation of CKD, receipt of blood pressure measurement at any time during follow-up, achieving a target blood pressure of 140/90 mm Hg or lower, and receiving a hemoglobin A1c test for monitoring diabetes during follow-up. Indicators in the domains of detection and recognition of CKD, testing and monitoring of kidney function (specifically, urine albumin to creatinine ratio testing), use of recommended medications, and appropriate monitoring after initiation of treatment with ACEIs or ARBs were not met. Only 6529 patients (18.4%) with CKD received a urine albumin test within 6 months of CKD diagnosis, and 3954 (39.4%) had a second measurement within 6 months of an abnormal baseline urine albumin level. Older age (≥85 years) and CKD stage 5 were significantly associated with not satisfying the criteria for the quality indicators across all domains. Across age categories, younger patients (aged 18-49 years) and older patients (≥75 years) were less likely to be tested for albuminuria (314 of 1689 patients aged 18-49 years [18.5%], 1983 of 11 919 patients aged 75-84 years [61.6%], and 614 of 5237 patients aged ≥85 years [11.7%] received the urine albumin to creatinine ratio test within 6 months of initial estimated glomerular filtration rate <60 mL/min per 1.73 m2; P < .001). Patients aged 18 to 49 years were less commonly prescribed recommended medications (222 of 2881 [7.7%]), whereas patients aged 75 to 84 years were prescribed ACEIs or ARBs most frequently (2328 of 5262 [44.2%]; P < .001). Conclusions and Relevance: The findings suggest that management of CKD across primary care practices in Canada varies according to quality indicator. This study revealed potential priority areas for quality improvement initiatives in Canadian primary care practices.

Indexed as

Primary Health CareAdultAgedAged, 80 and overAlbuminuriaCanadaComorbidityCross-Sectional StudiesDiabetes MellitusDisease ManagementFemaleGlomerular Filtration RateHumansHypertensionMaleMiddle Aged

Identifiers

PMID31483474
PMCPMC6727682
OpenAlexW2971376012

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.