ReviewCurrent opinion in oncology2019
Treatment of cognitive deficits in brain tumour patients: current status and future directions.
Review in Current opinion in oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 5 syntheses or guidelines pooled it, 108 citations in OpenAlex.
- Redefining neurocognitive outcomes after radiation for brain metastases: a patient-level meta-analysis of recovery following initial decline.Journal of the National Cancer Institute · 2026Pooled it
- Can cognitive function tests discriminate between patients with glioma and healthy controls prior to treatment? A systematic review.PloS one · 2025Pooled it
- Impact of Cognitive Rehabilitation on Cognitive and Functional Outcomes in Adult Cancer Survivors: A Systematic Review.Seminars in oncology nursing · 2024Pooled it
- Interventions for preventing and ameliorating cognitive deficits in adults treated with cranial irradiation.The Cochrane database of systematic reviews · 2022Pooled it
- Brain metastases: A Society for Neuro-Oncology (SNO) consensus review on current management and future directions.Neuro-oncology · 2022Guideline
- Impact of consultation recordings on patient-reported outcomes in patients with brain tumors: a parallel randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Trial
- Working memory training in pediatric brain tumor survivors after recent diagnosis: Challenges and initial effects.Applied neuropsychology. ChildTrial
- γ-radiation reduces phosphorylated-tau in rhesus macaque brains: potential implications for Alzheimer's disease and other tauopathies.Alzheimer's research & therapy · 2026Article
- A brain-penetrant chimeric protein combines direct glioma targeting with myeloid cell-mediated immune reprogramming.Journal of translational medicine · 2026Article
- Feasibility and utility of a tablet-based digital neurocognitive assessment following radiosurgery for brain metastases.Scientific reports · 2026Article
- γ-Radiation Reduces phosphorylated-Tau in RhesusMacaque Brains: Potential Implications forAlzheimer's Disease and other Tauopathies.Research square · 2026Article
- Integrating a novel tablet-based digital neurocognitive assessment tool in brain metastases patients.Journal of neuro-oncology · 2025Observational
- Brain, Cognition, and Psychoanalysis: A Scoping Review.Brain sciences · 2025Review
- Chronic Neurological Complications of Brain Tumors and Brain Tumor Treatments.Current neurology and neuroscience reports · 2025Review
- Understanding veterans' experiences with lung cancer and psychological distress: A multimethod approach.Psychological services · 2024Article
- Symptom experience and symptom distress in patients with malignant brain tumor treated with proton therapy: A five-year follow-up study.Technical innovations & patient support in radiation oncology · 2024Article
- Performance of the Wisconsin Card Sorting Test in Oncopediatric Patients in an Oncology Unit in Cali, Colombia: A Cross-Sectional Observational Study.Children (Basel, Switzerland) · 2024Article
- "Why am I still suffering?": Experience of long-term fatigue and neurocognitive changes in oropharyngeal cancer survivors following (chemo)radiotherapy.Technical innovations & patient support in radiation oncology · 2024Article
- Rehabilitation in People Living with Glioblastoma: A Narrative Review of the Literature.Cancers · 2024Review
- Executive Functions in a Patient with Low-Grade Glioma of the Central Nervous System: A Case Report.Tomography (Ann Arbor, Mich.) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewIncreased life expectancy in brain tumour patients had led to the need for strategies that preserve and improve cognitive functioning, as many patients suffer from cognitive deficits. The tumour itself, as well as antitumor treatment including surgery, radiotherapy and chemotherapy, supportive treatment and individual patient factors are associated with cognitive problems. Here, we review the recent literature on approaches that preserve and improve cognitive functioning, including pharmacological agents and rehabilitation programs. RECENT
findingsMinimizing cognitive dysfunction and improving cognitive functioning in brain tumour patients may be achieved both by preserving cognitive functioning during antitumor treatment, including techniques such as awake brain surgery, less invasive radiation therapies such as stereotactic radiotherapy and proton therapy, as well as with interventions including cognitive rehabilitation programmes. Novel rehabilitation programs including computer-based cognitive rehabilitation therapy (CRT) programmes that can be adjusted to the specific patient needs and can be administered at home are promising. Furthermore, personalized/precision medicine approaches to identify patients who are at risk for cognitive decline may facilitate effective treatment strategies in the future. SUMMARY: Cognitive functioning has gained greater awareness in the neuro-oncological community, and methods to preserve and improve cognitive functioning have been explored. Rehabilitation programmes for brain tumour patients should be further developed and referred to in clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.