Evidence map›Paper›PMID 31483239›Full record

ArticleThe Journal of general virology2019

Updated classification of norovirus genogroups and genotypes.

Preeti Chhabra, Miranda de Graaf, Gabriel I Parra, Martin Chi-Wai Chan, Kim Green, Vito Martella, Qiuhong Wang, Peter A White, Kazuhiko Katayama, Harry Vennema and 2 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in The Journal of general virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 480 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
480citing papers in PubMed, 4 pooled it
64.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

480 citing papers in PubMed, 4 syntheses or guidelines pooled it, 892 citations in OpenAlex.

  1. Pooled it
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  5. Article
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  11. Case-Fatality Risk of Norovirus, England, 2022-2025.Emerging infectious diseases · 2026
    Article
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  13. Article
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  15. Article
  16. Review
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  18. Article
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420 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 6 countries.

Preeti ChhabraDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Miranda de GraafDepartment of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.
Gabriel I ParraDivision of Viral Products, Food and Drug Administration, Silver Spring, MD, USA.
Martin Chi-Wai ChanDepartment of Microbiology, Stanley Ho Centre for Emerging Infectious Diseases and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, PR China.
Kim GreenCaliciviruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Vito MartellaDepartment of Veterinary Medicine, University of Bari Aldo Moro, Bari, Italy.
Qiuhong WangDepartment of Veterinary Preventive Medicine, The Ohio State University, Wooster, OH, USA.
Peter A WhiteSchool of Biotechnology and Biomolecular Sciences, Faculty of Science, University of New South Wales, Sydney 2052, Australia.
Kazuhiko KatayamaLaboratory of Viral infection I, Kitasato Institute for Life Sciences Graduate School of Infection Control Sciences, Kitasato University, Tokyo, Japan.
Harry VennemaDivision for Virology, Centre for Infectious Diseases Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Marion P G KoopmansDepartment of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.
Jan VinjéDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Centers for Disease Control and Prevention · USErasmus MC · NLChinese University of Hong Kong · HKKitasato University · JPNational Institute for Public Health and the Environment · NLNational Institutes of Health · USThe Ohio State University · USUnited States Food and Drug Administration · USUniversity of Bari Aldo Moro · ITUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noroviruses are genetically diverse RNA viruses associated with acute gastroenteritis in mammalian hosts. Phylogenetically, they can be segregated into different genogroups as well as P (polymerase)-groups and further into genotypes and P-types based on amino acid diversity of the complete VP1 gene and nucleotide diversity of the RNA-dependent RNA polymerase (RdRp) region of ORF1, respectively. In recent years, several new noroviruses have been reported that warrant an update of the existing classification scheme. Using previously described 2× standard deviation (sd) criteria to group sequences into separate clusters, we expanded the number of genogroups to 10 (GI-GX) and the number of genotypes to 48 (9 GI, 27 GII, 3 GIII, 2 GIV, 2 GV, 2 GVI and 1 genotype each for GVII, GVIII, GIX [formerly GII.15] and GX). Viruses for which currently only one sequence is available in public databases were classified into tentative new genogroups (GNA1 and GNA2) and genotypes (GII.NA1, GII.NA2 and GIV.NA1) with their definitive assignment awaiting additional related sequences. Based on nucleotide diversity in the RdRp region, noroviruses can be divided into 60 P-types (14 GI, 37 GII, 2 GIII, 1 GIV, 2 GV, 2 GVI, 1 GVII and 1 GX), 2 tentative P-groups and 14 tentative P-types. Future classification and nomenclature updates will be based on complete genome sequences and will be coordinated and disseminated by the international norovirus classification-working group.

Indexed as

Caliciviridae InfectionsGastroenteritisGenome, ViralGenotypeHumansNorovirusPhylogeny2xSD criteriaacute gastroenteritisclassificationgenogroupgenotypeNorovirusP-groupP-type

Identifiers

PMID31483239
PMCPMC7011714
OpenAlexW2975573382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.