Evidence map›Paper›PMID 31483156›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2019

Heat therapy reduces sympathetic activity and improves cardiovascular risk profile in women who are obese with polycystic ovary syndrome.

Brett R Ely, Michael A Francisco, John R Halliwill, Samantha D Bryan, Lindan N Comrada, Emily A Larson, Vienna E Brunt, Christopher T Minson

2 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06932250 narecruitingnot on this mapstarted 2025, after this paper: background citation

Vascular and Neural Mechanisms of Chronic Leg Heating in Pregnant Women With Obesity

TypeinterventionalSponsorUniversity of Texas Southwestern Medical CenterRan2025 to 2030Enrolled118ConditionsHigh-risk PregnancyArmsLeg heating
NCT07158047 narecruitingnot on this mapstarted 2022, after this paper: background citation

Targeting Hypertension and Insulin Resistance With Heat Therapy

TypeinterventionalSponsorUniversity of OregonRan2022 to 2026Enrolled20ConditionsObesity (Disorder)ArmsHeat therapy
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

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  6. Effects of regular sauna bathing in conjunction with exercise on cardiovascular function: a multi-arm, randomized controlled trial.American journal of physiology. Regulatory, integrative and comparative physiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Brett R ElyDepartment of Human Physiology, University of Oregon, Eugene, Oregon.ORCID 0000-0002-8062-4475
Michael A FranciscoDepartment of Human Physiology, University of Oregon, Eugene, Oregon.
John R HalliwillDepartment of Human Physiology, University of Oregon, Eugene, Oregon.ORCID 0000-0003-3001-1715
Samantha D BryanDepartment of Human Physiology, University of Oregon, Eugene, Oregon.
Lindan N ComradaDepartment of Human Physiology, University of Oregon, Eugene, Oregon.
Emily A LarsonDepartment of Human Physiology, University of Oregon, Eugene, Oregon.
Vienna E BruntDepartment of Human Physiology, University of Oregon, Eugene, Oregon.
Christopher T MinsonDepartment of Human Physiology, University of Oregon, Eugene, Oregon.ORCID 0000-0003-3459-3708
University of Oregon · US

Funding

Heat Therapy versus Exercise Training in HypertensionR01HL144128 · NHLBI · UNIVERSITY OF OREGON · PI HALLIWILL, JOHN R., MINSON, CHRISTOPHER TODD · 2018 to 2021
$2.6M
NHLBI NIH HHS R01 HL144128
6 · The paper itself

Abstract

Polycystic ovary syndrome (PCOS) affects up to 15% of women and is associated with increased risk of obesity and cardiovascular disease. Repeated passive heat exposure [termed "heat therapy" (HT)] is a lifestyle intervention with the potential to reduce cardiovascular risk in obesity and PCOS. Women with obesity (

Indexed as

Hot TemperatureBlood PressureCardiovascular DiseasesCardiovascular SystemFemaleHumansObesityPolycystic Ovary SyndromeRisk FactorsSympathetic Nervous Systemheat acclimationischemia reperfusion injurymuscle sympathetic nerve activitythermal therapyvascular function

Identifiers

PMID31483156
PMCPMC8424543
OpenAlexW2972104810

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.