Trial reportBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica2019
A newly designed intensive caregiver education program reduces cognitive impairment, anxiety, and depression in patients with acute ischemic stroke.
Trial report in Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Integrated care management for patients following acute stroke: a systematic review.QJM : monthly journal of the Association of Physicians · 2025Pooled it
- Pooled it
- Occupational therapy for cognitive impairment in stroke patients.The Cochrane database of systematic reviews · 2022Pooled it
- A study on the effect of using the video teach-back method in continuous nursing care of stroke patients.Frontiers in public health · 2024Trial
- Reminiscence therapy serves as an optional nursing care strategy in attenuating cognitive impairment, anxiety, and depression in acute ischemic stroke patients.Irish journal of medical science · 2022Trial
- Reminiscence therapy-based care program relieves post-stroke cognitive impairment, anxiety, and depression in acute ischemic stroke patients: a randomized, controlled study.Irish journal of medical science · 2021Trial
- Long-Term Effect of Intensive Education in Patients With First-Ever Ischemic Stroke.Journal of the American Heart Association · 2026Article
- Review
- Carotid revascularization improves cognition in patients with carotid stenosis.Scientific reports · 2025Article
- Article
- Early Occupational Therapy Intervention Programme and Coping Strategies and Burden in Caregivers of People with Sub-Acute Stroke: A Randomised Controlled Trial.Journal of personalized medicine · 2024Article
- Memory-Guided Saccades in Subacute and Chronic Stroke: Secondary Data Analysis of the N-PEP-12 Clinical Study.Biomedicines · 2024Article
- Home-based educational interventions for family caregivers of older adults after stroke: a scoping review.Revista da Escola de Enfermagem da U S P · 2024Article
- Effects of "two-heart" nursing mode on the psychological state and quality of life of stroke patients.BMC neurology · 2023Article
- Review
- Outcome of management based on "1+X" model in a health examination center.American journal of translational research · 2023Article
- An Evidence-Based Nursing Intervention Decreases Anxiety, Depression, Sleep Quality and Somatic Symptoms of Patients with Acute Ischemic Stroke.Neuropsychiatric disease and treatment · 2022Article
- Correlation of common inflammatory cytokines with cognition impairment, anxiety, and depression in acute ischemic stroke patients.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022Article
- 4-Hydroxy-3,5-di-tret-butyl cinnamic acid restores the activity of the hippocampal mitochondria in rats under permanent focal cerebral ischemia.Iranian journal of basic medical sciences · 2021Article
- Effect of Case-Based Small-Group Learning on Care Workers' Emergency Coping Abilities.International journal of environmental research and public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to evaluate the effect of a newly designed intensive caregiver education program (ICEP) on reducing cognitive impairment, anxiety, and depression in acute ischemic stroke (AIS) patients. One hundred and ninety-six AIS patients were divided into ICEP group and Control group in a 1:1 ratio using blocked randomization method. In the ICEP group, the caregivers received ICEP, while in the Control group caregivers received usual education and guidance. All patients received conventional rehabilitation treatment. Cognitive impairment (assessed by Mini Mental State Examination (MMSE) score and Montreal Cognitive Assessment (MoCA) score), anxiety (assessed by Hospital Anxiety and Depression Scale (HADS)-A score and Self-rating Anxiety Scale (SAS) score), and depression (assessed by HADS-D score and Self-rating Depression Scale (SDS) score) were assessed at baseline (M0), 3 months (M3), 6 months (M6), and 12 months (M12). Cognitive impairment score at M12 and cognitive impairment score change (M12-M0) were increased, while cognitive impairment rate at M12 was reduced in the ICEP group compared with the Control group. Anxiety score change (M12-M0), anxiety score at M12, and anxiety rate at M12 were decreased in the ICEP group compared with the Control group. Depression score change (M12-M0), depression score at M12, and depression rate at M12 were lower in the ICEP group compared with the Control group. Further subgroup analysis based on baseline features also provided similar results. In conclusion, ICEP effectively reduced cognitive impairment, anxiety, and depression in AIS patients.
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