ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2019
Severity of Desaturations Reflects OSA-Related Daytime Sleepiness Better Than AHI.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.
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Who cites it
59 citing papers in PubMed, 1 synthesis or guideline pooled it, 112 citations in OpenAlex.
- Obstructive sleep apnea and attention deficits: A systematic review of magnetic resonance imaging biomarkers and neuropsychological assessments.Brain and behavior · 2023Pooled it
- Trial
- Differential associations of arousals and respiratory events on oxygen desaturation and resaturation parameters in sleep.Sleep & breathing = Schlaf & Atmung · 2026Article
- Recognition of Obstructive Sleep Apnea: An Exploratory Bayesian Modeling Analysis.Journal of personalized medicine · 2026Article
- Clinical Characteristics of Moderate-to-Severe Obstructive Sleep Apnea: A Cross-sectional Analysis of 12,715 Adults from the TURKAPNE Cohort.Thoracic research and practice · 2026Article
- Hypoxic Burden in Children With Sleep-Disordered Breathing: Determinants and Correlates.Journal of sleep research · 2026Article
- Relationship between body weight and daytime sleepiness in patients with untreated OSA: The role of hypoventilation due to obesity.Sleep & breathing = Schlaf & Atmung · 2026Article
- Identification of Comorbidities in Obstructive Sleep Apnea Using Diverse Data and a One-Dimensional Convolutional Neural Network.Sensors (Basel, Switzerland) · 2026Observational
- Polysomnographic characteristics of excessive daytime sleepiness in postmenopausal women with obstructive sleep apnea.Frontiers in sleep · 2026Article
- Determinants of MSLT- defined sleepiness in OSA patients with neuropsycological findings.Sleep & breathing = Schlaf & Atmung · 2025Article
- Obstructive sleep apnea and polysomnographic predictors of neuropsychological performance two years after injury in a prospective cohort of adults with traumatic brain injury.The Clinical neuropsychologist · 2025Article
- AttenCRF-U: Joint Detection of Sleep-Disordered Breathing and Leg Movements in OSA Patients.Bioengineering (Basel, Switzerland) · 2025Article
- Article
- The Hourly Apnea-Hypopnea Duration Better Correlates with OSA-Related Nocturnal Hypoxemia and Excessive Daytime Sleepiness Rather Than AHI.Nature and science of sleep · 2025Article
- Article
- Article
- The effect of hypoxia on interoception in patient with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2024Article
- Sleep Hypoxemia as a Predictor of Mortality in Patients with Sleep Apnea: A Secondary Analysis of the Sleep Heart Health Study.CHEST pulmonary · 2024Article
- Sleep stage continuity is associated with objective daytime sleepiness in patients with suspected obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- Article
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Authors and funding
7 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesThe aim was to investigate how the severity of apneas, hypopneas, and related desaturations is associated with obstructive sleep apnea (OSA)-related daytime sleepiness.
methodsMultiple Sleep Latency Tests and polysomnographic recordings of 362 patients with OSA were retrospectively analyzed and novel diagnostic parameters (eg, obstruction severity and desaturation severity), incorporating severity of apneas, hypopneas, and desaturations, were computed. Conventional statistical analysis and multivariate analyses were utilized to investigate connection of apnea-hypopnea index (AHI), oxygen desaturation index (ODI), conventional hypoxemia parameters, and novel diagnostic parameters with mean daytime sleep latency (MSL).
resultsIn the whole population, 10% increase in values of desaturation severity (risk ratio = 2.01, P < .001), obstruction severity (risk ratio = 2.18, P < .001) and time below 90% saturation (t
conclusionsSeverity of sleep-related breathing cessations and desaturations is a stronger contributor to daytime sleepiness than AHI or ODI and therefore should be included in the diagnostics and severity assessment of OSA. CITATION: Kainulainen S, Töyräs J, Oksenberg A, Korkalainen H, Sefa S, Kulkas A, Leppänen T. Severity of desaturations reflects OSA-related daytime sleepiness better than AHI. J Clin Sleep Med. 2019;15(8):1135-1142.
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