Evidence map›Paper›PMID 31482831›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2019

On the Association Between Sleep Quality and Arterial Stiffness: A Population Study in Community-Dwelling Older Adults Living in Rural Ecuador (The Atahualpa Project).

Oscar H Del Brutto, Robertino M Mera, Ernesto Peñaherrera, Aldo F Costa, Rubén Peñaherrera, Pablo R Castillo

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01627600 (The Atahualpa Project, a 3-phase Epidemiologic Survey), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01627600 completednot on this map

The Atahualpa Project, a 3-phase Epidemiologic Survey

TypeobservationalSponsorHospital Clínica KennedyRan2012 to 2012Enrolled642ConditionsStroke, Ischemic Heart Disease
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Review
  5. Article
  6. Article
  7. Vascular ageing: moving from bench towards bedside.European journal of preventive cardiology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Oscar H Del BruttoSchool of Medicine, Universidad Espíritu Santo - Ecuador, Guayaquil, Ecuador.
Robertino M MeraDepartment of Epidemiology, Gilead Sciences, Inc., Foster City, California.
Ernesto PeñaherreraDepartment of Cardiology, Hospital Luis Vernaza, Guayaquil, Ecuador.
Aldo F CostaSchool of Medicine, Universidad Espíritu Santo - Ecuador, Guayaquil, Ecuador.
Rubén PeñaherreraSchool of Medicine, Universidad Espíritu Santo - Ecuador, Guayaquil, Ecuador.
Pablo R CastilloSleep Disorders Center, Mayo Clinic School of Medicine, Jacksonville, Florida.
Universidad de Especialidades Espíritu Santo · ECGilead Sciences (United States) · USHospital Luis Vernaza · ECJacksonville College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectivesEvidence of an association between atherosclerosis and sleep quality is limited and has not been studied in remote rural settings, where living conditions are different than in urban centers. We aimed to assess the relationship between the aortic pulse wave velocity (PWV) and sleep quality in older adults living in rural Ecuador.

methodsAtahualpa residents aged 60 years or older identified during door-to-door surveys, who consented to participate, underwent face-to-face interviews with the Pittsburgh Sleep Quality Index (PSQI) to assess sleep quality. Aortic PWV determinations were performed for arterial stiffness estimation (as a surrogate of atherosclerosis).

resultsA total of 303 individuals were included (mean age: 70.3 ± 7.8 years; 59% women). Univariate logistic regression showed a significant association between the aortic PWV and poor sleep quality (odds ratio [OR] 1.22; 95% confidence interval [CI] 1.07-1.39; P = .003). A multivariate logistic regression model, adjusted for demographics, cardiovascular risk factors, oily fish intake and psychological distress showed a significant association between increased PWV and poor sleep quality (OR 1.59; 95% CI 1.12-2.25; P = .009). Similar significance was noted when the model was adjusted for neuroimaging signatures of cerebral small-vessel disease and stroke (OR 1.47; 95% CI 1.07-2.03; P = .019).

conclusionsThis study shows a significant independent association between the aortic PWV and poor sleep quality in older adults living in rural Ecuador. Results provide more insights into the relevance of the impact of sleep disorders on cardiovascular diseases. CLINICAL

trial registrationThe Atahualpa Project has been registered at ClinicalTrials.gov. The identifier number is NCT01627600, and the date was: 10/02/2012. CITATION: Del Brutto OH, Mera RM, Peñaherrera E, Costa AF, Peñaherrera R, Castillo PR. On the association between sleep quality and arterial stiffness: a population study in community-dwelling older adults living in rural ecuador (the atahualpa project). J Clin Sleep Med. 2019;15(8):1101-1106.

Indexed as

Vascular StiffnessAgedAtherosclerosisEcuadorFemaleHumansIndependent LivingLogistic ModelsMaleRisk FactorsRural PopulationSleepSurveys and Questionnairesaortic pulse wave velocityarterial stiffnessatherosclerosisPittsburgh Sleep Quality Indexsleep quality

Identifiers

PMID31482831
PMCPMC6707051
OpenAlexW2967920857

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.