Evidence map›Paper›PMID 31482721›Full record

ArticleAntioxidants & redox signaling2019

Polyubiquitin Chains Linked by Lysine Residue 48 (K48) Selectively Target Oxidized Proteins

Sandhya Manohar, Samson Jacob, Jade Wang, Keira A Wiechecki, Hiromi W L Koh, Vanessa Simões, Hyungwon Choi, Christine Vogel, Gustavo M Silva

Open access · greenAbstract read
In one paragraph

Article in Antioxidants & redox signaling, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Sandhya ManoharDepartment of Biology, Center for Genomics and Systems Biology, New York University, New York, New York.
Samson JacobDepartment of Biology, Center for Genomics and Systems Biology, New York University, New York, New York.
Jade WangDepartment of Biology, Center for Genomics and Systems Biology, New York University, New York, New York.
Keira A WiecheckiDepartment of Biology, Center for Genomics and Systems Biology, New York University, New York, New York.
Hiromi W L KohDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Vanessa SimõesDepartment of Biology, Duke University, Durham, North Carolina.
Hyungwon ChoiDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Christine VogelDepartment of Biology, Center for Genomics and Systems Biology, New York University, New York, New York.
Gustavo M SilvaDepartment of Biology, Duke University, Durham, North Carolina.
New York University · USDuke University · USNational University of Singapore · SG

Funding

Next generation gene expression analysisR35GM127089 · NIGMS · NEW YORK UNIVERSITY · PI Christine Vogel · 2018 to 2026
$4.0M
Defining the roles of ubiquitination during the environmental stress responseR00ES025835 · NIEHS · DUKE UNIVERSITY · PI SILVA, GUSTAVO M · 2018 to 2020
$905k
Defining the roles of ubiquitination during the environmental stress responseK99ES025835 · NIEHS · NEW YORK UNIVERSITY · PI SILVA, GUSTAVO M · 2015 to 2016
$205k
NIEHS NIH HHS K99 ES025835NIEHS NIH HHS R00 ES025835NIGMS NIH HHS R35 GM127089
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Energy MetabolismHumansLysineOxidation-ReductionPolyubiquitinProteomicsUbiquitinLysinePolyubiquitinUbiquitinoxidationoxidative stressprotein degradationproteomicsubiquitin

Identifiers

PMID31482721
PMCPMC6798811
OpenAlexW2971409314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.