Evidence map›Paper›PMID 31482429›Full record

GuidelineEuropean journal of nuclear medicine and molecular imaging2020

EANM practice guideline for PET/CT imaging in medullary thyroid carcinoma.

Luca Giovanella, Giorgio Treglia, Ioannis Iakovou, Jasna Mihailovic, Frederik A Verburg, Markus Luster

Abstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 2 pooled it
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 123 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Covalent FAPI Imaging-Guided Precision Surgery in Patients with Medullary Thyroid Carcinoma: A Phase II Clinical Trial.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
    Trial
  4. Application of theranostics in thyroid cancer management.The Journal of clinical endocrinology and metabolism · 2026
    Review
  5. Article
  6. Clinical performance of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
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  14. Review
  15. Comparison ofFrontiers in endocrinology · 2026
    Article
  16. FDG PET Hybrid Imaging.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  17. Article
  18. Review
  19. The value ofCancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
  20. Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Luca GiovanellaClinic for Nuclear Medicine and Thyroid Competence Centre, Imaging Institute of Southern Switzerland, Via Ospedale 6, CH-6500, Bellinzona, Switzerland. Luca.Giovanella@eoc.ch.ORCID 0000-0003-0230-0974
Giorgio TregliaClinic for Nuclear Medicine and Thyroid Competence Centre, Imaging Institute of Southern Switzerland, Via Ospedale 6, CH-6500, Bellinzona, Switzerland.
Ioannis IakovouAcademic Department of Nuclear Medicine, Papageorgiu Hospital, Thessaloniki, Greece.
Jasna MihailovicDepartment of Nuclear Medicine, Oncology Institute of Vojvodina, Sremska Kamenica, Serbia.
Frederik A VerburgDepartment of Nuclear Medicine, University Hospital Marburg, Marburg, Germany.
Markus LusterDepartment of Nuclear Medicine, University Hospital Marburg, Marburg, Germany.
Laboratory for Biomedical Neurosciences · CHPhilipps University of Marburg · DEOncology Institute of Vojvodina · RSPapageorgiou General Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedullary thyroid carcinoma (MTC) is a malignant tumour derived from the para-follicular thyroid C cells. It may occur in sporadic or hereditary forms and surgery represent the primary cure.

methodsUltrasound examination and, in selected cases, cross-sectional anatomic imaging procedures, are adopted to stage the disease before primary surgery while different anatomic/morphologic and functional/molecular imaging procedures can be adopted in detecting persistent/recurrent disease. Positron emitting radiopharmaceuticals including fluorine-18 fluorodeoxyglucose (

conclusionsThis practice guideline from the Thyroid Committee of the European Association of Nuclear Medicine (EANM), with involvement of external experts, provides recommendations based on updated literature's evidences. The purpose of this practice guideline is to assist imaging specialists and clinicians in recommending, performing and interpreting the results of PET/CT with various radiopharmaceuticals in patients with MTC.

Indexed as

Nuclear MedicineThyroid NeoplasmsCross-Sectional StudiesFluorodeoxyglucose F18HumansPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadiopharmaceuticalsFluorodeoxyglucose F18RadiopharmaceuticalsDihydroxyphenylalanineFluorodeoxyglucoseMedullary thyroid carcinomaPET/CTSomatostatin

Identifiers

PMID31482429
OpenAlexW2971811906

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.