Evidence map›Paper›PMID 31482358›Full record

ArticleSurgical endoscopy2020

Robotic and per-oral endoscopic myotomy have fewer technical complications compared to laparoscopic Heller myotomy.

Aman B Ali, Najah A Khan, Duc T Nguyen, Ray Chihara, Edward Y Chan, Edward A Graviss, Brian J Dunkin, Min P Kim

Registry-linked trialAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06290882 (Endoscopic Versus Robotic Myotomy for Treatment of Achalasia), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06290882 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Endoscopic Versus Robotic Myotomy for Treatment of Achalasia (ERMA Trial)

TypeinterventionalSponsorGermans Trias i Pujol HospitalRan2024 to 2027Enrolled144ConditionsAchalasia CardiaArmsRobotic Heller Myotomy, Peroral Endoscopic Myotomy
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Article
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  8. Observational
  9. Review
  10. Mixed Esophageal Disease (MED): A New Concept.Digestive diseases and sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Aman B AliDivision of Thoracic Surgery, Department of Surgery, Houston Methodist Hospital, 6550 Fannin Street, Suite 1661, Houston, TX, 77030, USA.
Najah A KhanDivision of Thoracic Surgery, Department of Surgery, Houston Methodist Hospital, 6550 Fannin Street, Suite 1661, Houston, TX, 77030, USA.
Duc T NguyenDepartment of Pathology & Genomic Medicine, Houston Methodist Hospital, Houston, TX, USA.ORCID http://orcid.org/0000-0002-5059-4404
Ray ChiharaDivision of Thoracic Surgery, Department of Surgery, Houston Methodist Hospital, 6550 Fannin Street, Suite 1661, Houston, TX, 77030, USA.
Edward Y ChanDivision of Thoracic Surgery, Department of Surgery, Houston Methodist Hospital, 6550 Fannin Street, Suite 1661, Houston, TX, 77030, USA.
Edward A GravissDepartment of Pathology & Genomic Medicine, Houston Methodist Hospital, Houston, TX, USA.ORCID http://orcid.org/0000-0003-1024-5813
Brian J DunkinDepartment of Surgery, Weill Cornell Medical College, Houston Methodist Hospital, Houston, TX, USA.
Min P KimDivision of Thoracic Surgery, Department of Surgery, Houston Methodist Hospital, 6550 Fannin Street, Suite 1661, Houston, TX, 77030, USA. mpkim@houstonmethodist.org.ORCID http://orcid.org/0000-0003-0941-8609
Houston Methodist · USCornell University · USMethodist Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAchalasia is an uncommon disease treated by decreasing the lower esophageal sphincter resting pressure. This study compared the safety and efficacy of esophago-gastric myotomy via laparoscopic, robotic, and per-oral endoscopic approaches.

methodsA retrospective review of data on patients with achalasia or other esophageal dysmotility disorder undergoing laparoscopic, robotically assisted, or per-oral endoscopic myotomy (POEM) procedures between 2013 and 2017 was performed. Patient demographics, comorbidities, procedure details, length of stay, 30-day readmission rate, and combined technical complication (full-thickness injury, conversion to open, and delayed perforation) were compared. Multiple logistic regression analysis was performed to determine which factors contributed to combined technical complication.

resultsThere were 171 patients who underwent esophago-gastric myotomy with 161 (94.2%) having achalasia. There were 40 laparoscopic Heller myotomies with partial fundoplication, 44 robotic Heller myotomies with partial fundoplication, and 87 POEM procedures performed during the study period. Baseline statistical differences were found among the groups in regard to gastroesophageal reflux symptoms, arrhythmia, hypertension, and congestive heart failure. Laparoscopic Heller myotomy had significantly higher combined technical complications (7, 17.5%) compared to robotically assisted Heller myotomy (0, 0%) and POEM (1, 1.1%). Multivariate analysis showed that laparoscopic Heller myotomy (OR 32.22; 95% CI 2.66, 389.83; p = 0.01), myocardial infarction (OR 27.94; 95% CI 1.66, 471.10; p = 0.02), and history of smoking (OR 8.87; 95% CI 1.29, 61.15; p = 0.03) were risks for developing combined technical complications.

conclusionRobotically assisted Heller myotomy and POEM are safe and efficacious treatments for achalasia with lower rates of technical complications compared to laparoscopic Heller myotomy. With the advancements in endoscopic instruments and robotic surgery, POEM and robotically assisted Heller myotomy should be considered in the treatment of achalasia and esophageal dysmotility disorders.

Indexed as

Esophageal AchalasiaEsophageal Sphincter, LowerFemaleFundoplicationHeller MyotomyHumansLaparoscopyLength of StayMaleMiddle AgedMultivariate AnalysisPatient ReadmissionPostoperative ComplicationsPyloromyotomyRetrospective StudiesRobotic Surgical ProceduresAchalasiaEsophago-gastric myotomyLaparoscopic Heller myotomyPer-oral endoscopic myotomyPOEMRobotic-assisted Heller myotomySurgical approach

Identifiers

PMID31482358
OpenAlexW2971846806

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.