Evidence map›Paper›PMID 31482336›Full record

ReviewAMB Express2019

The diversity and commonalities of the radiation-resistance mechanisms of Deinococcus and its up-to-date applications.

Mengmeng Jin, Anqi Xiao, Liying Zhu, Zhidong Zhang, He Huang, Ling Jiang

Open access · goldAbstract readReview
In one paragraph

Review in AMB Express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 86 citations in OpenAlex.

  1. Article
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  4. Article
  5. Review
  6. Draft genome sequence ofMicrobiology resource announcements · 2025
    Article
  7. Article
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  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Extremophilic microbial metabolism and radioactive waste disposal.Extremophiles : life under extreme conditions · 2023
    Review
  16. Article
  17. First characterization of cultivable extremophileFrontiers in microbiology · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mengmeng JinCollege of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 210019, People's Republic of China.
Anqi XiaoCollege of Chemical and Molecular Engineering, Nanjing Tech University, Nanjing, 210009, People's Republic of China.
Liying ZhuCollege of Chemical and Molecular Engineering, Nanjing Tech University, Nanjing, 210009, People's Republic of China. zlyhappy@njtech.edu.cn.
Zhidong ZhangInstitute of Microbiology, Xinjiang Academy of Agricultural Sciences, Urumqi, Xinjiang Uigur Autonomous Region, People's Republic of China.
He HuangCollege of Pharmaceutical Science, Nanjing Tech University, Nanjing, 210009, People's Republic of China.
Ling JiangCollege of Food Science and Light Industry, Nanjing Tech University, Nanjing, 210009, People's Republic of China. jiangling@njtech.edu.cn.
Nanjing Tech University · CNXinjiang Academy of Agricultural Sciences · CN

Funding

National High Technology Research and Development Program of China 2012AA021705National Key R&D Program of China 2018YFC1602800National Science Foundation of China U1603112Natural Science Foundation of Jiangsu Province BK20171461Natural Science Foundation of Jiangsu Province BK20180038the Six Talent Peaks Project in Jiangsu Province 2015-JY-009
6 · The paper itself

Abstract

Deinococcus is an extremophilic microorganism found in a wide range of habitats, including hot springs, radiation-contaminated areas, Antarctic soils, deserts, etc., and shows some of the highest levels of resistance to ionizing radiation known in nature. The highly efficient radiation-protection mechanisms of Deinococcus depend on a combination of passive and active defense mechanisms, including self-repair of DNA damage (homologous recombination, MMR, ER and ESDSA), efficient cellular damage clearance mechanisms (hydrolysis of damaged proteins, overexpression of repair proteins, etc.), and effective clearance of reactive oxygen species (ROS). Due to these mechanisms, Deinococcus cells are highly resistant to oxidation, radiation and desiccation, which makes them potential chassis cells for wide applications in many fields. This article summarizes the latest research on the radiation-resistance mechanisms of Deinococcus and prospects its biotechnological application potentials.

Indexed as

Anti-oxidationDeinococcusDNA repairIonizing radiation

Identifiers

PMID31482336
PMCPMC6722170
OpenAlexW2972238461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.