Evidence map›Paper›PMID 31482104›Full record

ArticleNeurophotonics2019

Nonresonant Raman spectroscopy of isolated human retina samples complying with laser safety regulations for

Clara Stiebing, Iwan W Schie, Florian Knorr, Michael Schmitt, Nanda Keijzer, Robert Kleemann, Izabella J Jahn, Martin Jahn, Amanda J Kiliaan, Laurin Ginner and 4 more

Abstract read
In one paragraph

Article in Neurophotonics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
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  4. Review
  5. Review
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  7. Article
  8. Review
  9. Article
  10. In Vivo Molecular Changes in the Retina of Patients With Multiple Sclerosis.Investigative ophthalmology & visual science · 2021
    Article
  11. Mammalian cell and tissue imaging using Raman and coherent Raman microscopy.Wiley interdisciplinary reviews. Systems biology and medicine · 2020
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Clara StiebingLeibniz Institute of Photonic Technology, Albert-Einstein-Straße, Jena, Germany.
Iwan W SchieLeibniz Institute of Photonic Technology, Albert-Einstein-Straße, Jena, Germany.ORCID https://orcid.org/0000-0003-0336-3168
Florian KnorrLeibniz Institute of Photonic Technology, Albert-Einstein-Straße, Jena, Germany.
Michael SchmittFriedrich Schiller University Jena, Institute of Physical Chemistry and Abbe Center of Photonics, Helmholtzweg, Jena, Germany.ORCID https://orcid.org/0000-0002-3807-3630
Nanda KeijzerNetherlands Organisation for Applied Scientific Research, Department of Metabolic Health Research, Zernikedreef, Leiden, The Netherlands.ORCID https://orcid.org/0000-0002-9901-5821
Robert KleemannNetherlands Organisation for Applied Scientific Research, Department of Metabolic Health Research, Zernikedreef, Leiden, The Netherlands.
Izabella J JahnLeibniz Institute of Photonic Technology, Albert-Einstein-Straße, Jena, Germany.
Martin JahnLeibniz Institute of Photonic Technology, Albert-Einstein-Straße, Jena, Germany.
Amanda J KiliaanRadboud University Medical Center, Institute for Brain, Cognition, and Behavior, Preclinical Imaging Center, Department of Anatomy Donders, Nijmegen, The Netherlands.
Laurin GinnerMedical University of Vienna, Center for Medical Physics and Biomedical Engineering, Vienna, Austria.ORCID https://orcid.org/0000-0003-1436-2048
Antonia LichteneggerMedical University of Vienna, Center for Medical Physics and Biomedical Engineering, Vienna, Austria.ORCID https://orcid.org/0000-0002-6422-9547
Wolfgang DrexlerMedical University of Vienna, Center for Medical Physics and Biomedical Engineering, Vienna, Austria.
Rainer A LeitgebMedical University of Vienna, Center for Medical Physics and Biomedical Engineering, Vienna, Austria.ORCID https://orcid.org/0000-0002-0131-4111
Jürgen PoppLeibniz Institute of Photonic Technology, Albert-Einstein-Straße, Jena, Germany.ORCID https://orcid.org/0000-0003-4257-593X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinal diseases, such as age-related macular degeneration, are leading causes of vision impairment, increasing in incidence worldwide due to an aging society. If diagnosed early, most cases could be prevented. In contrast to standard ophthalmic diagnostic tools, Raman spectroscopy can provide a comprehensive overview of the biochemical composition of the retina in a label-free manner. A proof of concept study of the applicability of nonresonant Raman spectroscopy for retinal investigations is presented. Raman imaging provides valuable insights into the molecular composition of an isolated

Indexed as

eye safety standardmacular pigmentoptical coherence tomographyRaman imagingretinal imaging

Identifiers

PMID31482104
PMCPMC6718815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.