Evidence map›Paper›PMID 31481887›Full record

ReviewFrontiers in synaptic neuroscience2019

Model-Based Inference of Synaptic Transmission.

Ola Bykowska, Camille Gontier, Anne-Lene Sax, David W Jia, Milton Llera Montero, Alex D Bird, Conor Houghton, Jean-Pascal Pfister, Rui Ponte Costa

Abstract readReview
In one paragraph

Review in Frontiers in synaptic neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The short-term plasticity of VIP interneurons in motor cortex.Frontiers in synaptic neuroscience · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Modeling the Short-Term Dynamics ofThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  10. Identifiability of a Binomial Synapse.Frontiers in computational neuroscience · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ola BykowskaComputational Neuroscience Unit, Department of Computer Science, SCEEM, Faculty of Engineering, University of Bristol, Bristol, United Kingdom.
Camille GontierDepartment of Physiology, University of Bern, Bern, Switzerland.
Anne-Lene SaxComputational Neuroscience Unit, Department of Computer Science, SCEEM, Faculty of Engineering, University of Bristol, Bristol, United Kingdom.
David W JiaDepartment of Physiology, Anatomy and Genetics, Centre for Neural Circuits and Behaviour, University of Oxford, Oxford, United Kingdom.
Milton Llera MonteroComputational Neuroscience Unit, Department of Computer Science, SCEEM, Faculty of Engineering, University of Bristol, Bristol, United Kingdom.
Alex D BirdErnst Strungmann Institute for Neuroscience in Cooperation With Max Planck Society, Frankfurt, Germany.
Conor HoughtonComputational Neuroscience Unit, Department of Computer Science, SCEEM, Faculty of Engineering, University of Bristol, Bristol, United Kingdom.
Jean-Pascal PfisterDepartment of Physiology, University of Bern, Bern, Switzerland.
Rui Ponte CostaComputational Neuroscience Unit, Department of Computer Science, SCEEM, Faculty of Engineering, University of Bristol, Bristol, United Kingdom.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Synaptic computation is believed to underlie many forms of animal behavior. A correct identification of synaptic transmission properties is thus crucial for a better understanding of how the brain processes information, stores memories and learns. Recently, a number of new statistical methods for inferring synaptic transmission parameters have been introduced. Here we review and contrast these developments, with a focus on methods aimed at inferring both synaptic release statistics and synaptic dynamics. Furthermore, based on recent proposals we discuss how such methods can be applied to data across different levels of investigation: from intracellular paired experiments to

Indexed as

model inferenceprobabilistic inferencequantal analysisshort-term synaptic plasticitysynaptic transmission

Identifiers

PMID31481887
PMCPMC6710341

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.