Evidence map›Paper›PMID 31481791›Full record

ArticleNature cell biology2019

CaMKII-δ9 promotes cardiomyopathy through disrupting UBE2T-dependent DNA repair.

Mao Zhang, Hua Gao, Dairu Liu, Xiaoming Zhong, Xiaolu Shi, Peng Yu, Li Jin, Yun Liu, Yajie Tang, Yunhu Song and 9 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. DNA damage and repair in cardiomyopathy: mechanisms and therapeutic opportunities.American journal of physiology. Heart and circulatory physiology · 2026
    Review
  13. Cytoplasmic CaMKIIδ-B prevents myocardial recovery in heart failure.bioRxiv : the preprint server for biology · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Role of CAMK2D in neurodevelopment and associated conditions.American journal of human genetics · 2024
    Article
  20. Mechanisms of RBM20 Cardiomyopathy: Insights From Model Systems.Circulation. Genomic and precision medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Mao ZhangState Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing, China.
Hua GaoDepartment of Clinical Laboratory, Peking University People's Hospital, Beijing, China.ORCID http://orcid.org/0000-0002-1029-1476
Dairu LiuState Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing, China.
Xiaoming ZhongInstitute of Molecular Medicine, Peking University, Beijing, China.
Xiaolu ShiExperimental Research Center, China Academy of Chinese Medical Sciences, Beijing, China.
Peng YuInstitute of Molecular Medicine, Peking University, Beijing, China.
Li JinState Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing, China.
Yun LiuDepartment of Cardiovascular Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yajie TangDepartment of Cardiovascular Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yunhu SongDepartment of Cardiovascular Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Jinghao LiuState Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing, China.
Xinli HuState Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing, China.
Chuan-Yun LiInstitute of Molecular Medicine, Peking University, Beijing, China.ORCID http://orcid.org/0000-0002-8008-8430
Lei SongNational Center for Protein Sciences (Beijing), State Key Laboratory of Proteomics, Institute of Lifeomics, Beijing, China.
Jun QinNational Center for Protein Sciences (Beijing), State Key Laboratory of Proteomics, Institute of Lifeomics, Beijing, China.
Fujian WuBeijing Laboratory for Cardiovascular Precision Medicine, The Key Laboratory of Remodeling-Related Cardiovascular Disease, Ministry of Education, Beijing Collaborative Innovation Center for Cardiovascular Disorders, Anzhen Hospital, Capital Medical University, Beijing, China.
Feng LanBeijing Laboratory for Cardiovascular Precision Medicine, The Key Laboratory of Remodeling-Related Cardiovascular Disease, Ministry of Education, Beijing Collaborative Innovation Center for Cardiovascular Disorders, Anzhen Hospital, Capital Medical University, Beijing, China.
Yan ZhangState Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing, China. zhangyan9876@pku.edu.cn.ORCID http://orcid.org/0000-0002-8322-467X
Rui-Ping XiaoState Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing, China.
Peking University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNBeijing Proteome Research Center · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ca

Indexed as

AnimalsCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2CardiomyopathiesDNA RepairHeart FailureHumansMiceMyocytes, CardiacPhosphorylationProtein IsoformsUbiquitin-Conjugating EnzymesCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2Protein IsoformsUBE2T protein, humanUbiquitin-Conjugating Enzymes

Identifiers

PMID31481791
OpenAlexW2976958398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.