Evidence map›Paper›PMID 31481539›Full record

ArticleCancer prevention research (Philadelphia, Pa.)2019

Differences in Genome-wide DNA Methylation Profiles in Breast Milk by Race and Lactation Duration.

Brittny C Davis Lynn, Clara Bodelon, Ruth M Pfeiffer, Hannah P Yang, Howard H Yang, Maxwell Lee, Peter W Laird, Mihaela Campan, Daniel J Weisenberger, Jeanne Murphy and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Cancer prevention research (Philadelphia, Pa.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. A biosocial return to race? A cautionary view for the postgenomic era.American journal of human biology : the official journal of the Human Biology Council · 2022
    Review
  3. [Peripheral bloodNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Brittny C Davis LynnNCI, NIH, Bethesda, Maryland. brittny.davis@nih.gov.
Clara BodelonNCI, NIH, Bethesda, Maryland.
Ruth M PfeifferNCI, NIH, Bethesda, Maryland.ORCID 0000-0001-7791-2698
Hannah P YangNCI, NIH, Bethesda, Maryland.
Howard H YangNCI, NIH, Bethesda, Maryland.
Maxwell LeeNCI, NIH, Bethesda, Maryland.
Peter W LairdVan Andel Research Institute, Grand Rapids, Michigan.ORCID 0000-0001-9117-3641
Mihaela CampanUniversity of Southern California, Los Angeles, California.
Daniel J WeisenbergerUniversity of Southern California, Los Angeles, California.
Jeanne MurphyNCI, NIH, Bethesda, Maryland.
Joshua N SampsonNCI, NIH, Bethesda, Maryland.ORCID 0000-0003-2875-3365
Eva P BrowneUniversity of Massachusetts at Amherst, Amherst, Massachusetts.
Douglas L AndertonUniversity of South Carolina, Columbia, South Carolina.
Mark E ShermanMayo Clinic Jacksonville, Jacksonville, Florida.
Kathleen F ArcaroUniversity of Massachusetts at Amherst, Amherst, Massachusetts.
Gretchen L GierachNCI, NIH, Bethesda, Maryland.
National Institutes of Health · USAmherst College · USUniversity of Southern California · USNemours Children's Clinic · USUniversity of South Carolina · USVan Andel Institute · US

Funding

Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

Black women in the United States are disproportionately affected by early-onset, triple-negative breast cancer. DNA methylation has shown differences by race in healthy and tumor breast tissues. We examined associations between genome-wide DNA methylation levels in breast milk and breast cancer risk factors, including race, to explain how this reproductive stage influences a woman's risk for, and potentially contributes to racial disparities in, breast cancer. Breast milk samples and demographic, behavioral, and reproductive data, were obtained from cancer-free, uniparous, and lactating U.S. black (

Indexed as

DNA MethylationEpigenesis, GeneticGenome, HumanLactationAdultBreastCpG IslandsFemaleHumansMilk, HumanRacial GroupsYoung Adult

Identifiers

PMID31481539
PMCPMC6825576
OpenAlexW2972097997

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.