Evidence map›Paper›PMID 31481409›Full record

ArticleInfection and immunity2019

Interleukin 17 Receptor E (IL-17RE) and IL-17C Mediate the Recruitment of Neutrophils during Acute

Patrick Steck, Felix Ritzmann, Anja Honecker, Giovanna Vella, Christian Herr, Rosmarie Gaupp, Markus Bischoff, Timotheus Speer, Thomas Tschernig, Robert Bals and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Patrick SteckDepartment of Internal Medicine V-Pulmonology, Allergology and Critical Care Medicine, Saarland University, Homburg, Germany.
Felix RitzmannDepartment of Internal Medicine V-Pulmonology, Allergology and Critical Care Medicine, Saarland University, Homburg, Germany.
Anja HoneckerDepartment of Internal Medicine V-Pulmonology, Allergology and Critical Care Medicine, Saarland University, Homburg, Germany.
Giovanna VellaDepartment of Internal Medicine V-Pulmonology, Allergology and Critical Care Medicine, Saarland University, Homburg, Germany.
Christian HerrDepartment of Internal Medicine V-Pulmonology, Allergology and Critical Care Medicine, Saarland University, Homburg, Germany.
Rosmarie GauppInstitute of Medical Microbiology and Hygiene, Saarland University, Homburg, Germany.
Markus BischoffInstitute of Medical Microbiology and Hygiene, Saarland University, Homburg, Germany.
Timotheus SpeerDepartment of Internal Medicine IV, Saarland University Medical Centre, Homburg, Germany.
Thomas TschernigInstitute of Anatomy and Cell Biology, Saarland University, Homburg, Germany.
Robert BalsDepartment of Internal Medicine V-Pulmonology, Allergology and Critical Care Medicine, Saarland University, Homburg, Germany.
Christoph BeisswengerDepartment of Internal Medicine V-Pulmonology, Allergology and Critical Care Medicine, Saarland University, Homburg, Germany christoph.beisswenger@uks.eu.
Saarland University · DEInstitute of Medical Microbiology and Hygiene · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutrophils contribute to lung injury in acute pneumococcal pneumonia. The interleukin 17 receptor E (IL-17RE) is the functional receptor for the epithelial-derived cytokine IL-17C, which is known to mediate innate immune functions. The aim of this study was to investigate the contribution of IL-17RE/IL-17C to pulmonary inflammation in a mouse model of acute

Indexed as

AnimalsCell DifferentiationFemaleGranulocytesInterleukin-17MiceMice, KnockoutNeutrophilsPneumonia, PneumococcalReceptors, Interleukin-17Streptococcus pneumoniaeIl17c protein, mouseInterleukin-17Receptors, Interleukin-17G-CSFhost defenseIL-17IL-17CIL-17RElung infectionneutrophilspneumoniasepsisStreptococcus pneumoniae

Identifiers

PMID31481409
PMCPMC6803337
OpenAlexW2971493423

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.