Evidence map›Paper›PMID 31481408›Full record

ArticleInfection and immunity2019

Immunomodulatory Effects of Lactobacillus plantarum on Inflammatory Response Induced by Klebsiella pneumoniae.

Marjolaine Vareille-Delarbre, Sylvie Miquel, Sophie Garcin, Thomas Bertran, Damien Balestrino, Bertrand Evrard, Christiane Forestier

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Meta-Analysis: Randomized Trials ofFrontiers in immunology · 2021
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Decoding Host-Pathogen Dynamics inAntibiotics (Basel, Switzerland) · 2026
    Review
  6. Article
  7. Outer Membrane Vesicles AttenuateMicroorganisms · 2025
    Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Journal of microbiology and biotechnology · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Oral Administration ofMicroorganisms · 2023
    Article
  19. Microbial Dysregulation of the Gut-Lung Axis in Bronchiectasis.American journal of respiratory and critical care medicine · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Marjolaine Vareille-DelarbreUniversité Clermont Auvergne, INRA, UNH, Unité de Nutrition Humaine, Laboratoire d'Immunologie, Clermont-Ferrand, France marjolaine.vareille-delarbre@uca.fr christiane.forestier@uca.fr.
Sylvie MiquelUniversité Clermont Auvergne, UMR CNRS 6023 LMGE, Laboratoire de Bactériologie, Clermont-Ferrand, France.
Sophie GarcinUniversité Clermont Auvergne, INRA, UNH, Unité de Nutrition Humaine, Laboratoire d'Immunologie, Clermont-Ferrand, France.
Thomas BertranUniversité Clermont Auvergne, INRA, UNH, Unité de Nutrition Humaine, Laboratoire d'Immunologie, Clermont-Ferrand, France.
Damien BalestrinoUniversité Clermont Auvergne, UMR CNRS 6023 LMGE, Laboratoire de Bactériologie, Clermont-Ferrand, France.ORCID 0000-0001-5378-0379
Bertrand EvrardUniversité Clermont Auvergne, INRA, UNH, Unité de Nutrition Humaine, Laboratoire d'Immunologie, Clermont-Ferrand, France.
Christiane ForestierUniversité Clermont Auvergne, UMR CNRS 6023 LMGE, Laboratoire de Bactériologie, Clermont-Ferrand, France marjolaine.vareille-delarbre@uca.fr christiane.forestier@uca.fr.
Université Clermont Auvergne · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some respiratory infections have been associated with dysbiosis of the intestinal microbiota. The underlying mechanism is incompletely understood, but cross talk between the intestinal microbiota and local immune cells could influence the immune response at distal mucosal sites. This has led to the concept of enhancing respiratory defenses by modulating the intestinal microbiota with exogenous supplementation of beneficial strains. In this study, we examined the effect of

Indexed as

AnimalsInflammationKlebsiella InfectionsKlebsiella pneumoniaeLactiplantibacillus plantarumMiceMice, Inbred C57BLPneumonia, BacterialProbioticsgut-lung axisinflammationLactobacillus

Identifiers

PMID31481408
PMCPMC6803346
OpenAlexW2970067733

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.