Evidence map›Paper›PMID 31481133›Full record

ArticleBMC research notes2019

Comorbidities and polypharmacy among HIV-positive patients aged 50 years and over: a case-control study.

José Antonio Mata-Marín, Moisés Hermilo Martínez-Osio, Carla I Arroyo-Anduiza, María de Los Ángeles Berrospe-Silva, Alberto Chaparro-Sánchez, Itzel Cruz-Grajales, Javier Enrique Cruz-Herrera, Luis Antonio Uribe-Noguez, Jesus E Gaytán-Martínez, Medardo Jerónimo-Morales

Abstract read
In one paragraph

Article in BMC research notes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

José Antonio Mata-MarínInfectious Diseases Department, Instituto Mexicano del Seguro Social, Hospital de Infectología, "La Raza" National Medical Center, IMSS, Seris y Jacarandas s/n, colonia la raza, Del Azcapotzalco, PO. 02990, Mexico City, Mexico. jamatamarin@gmail.com.ORCID http://orcid.org/0000-0002-5296-0287
Moisés Hermilo Martínez-OsioInternal Medicine Department, Hospital General, "La Raza" National Medical Center, IMSS, Mexico City, Mexico.
Carla I Arroyo-AnduizaClinical Pathology Department, Banco Central de Sangre, Hospital de Especialidades, "La Raza" National Medical Center, IMSS, Mexico City, Mexico.
María de Los Ángeles Berrospe-SilvaInfectious Diseases Department, Instituto Mexicano del Seguro Social, Unidad de Infectología "Juan I. Menchaca", Ext HGR 45, IMSS, Guadalajara, Jalisco, Mexico.
Alberto Chaparro-SánchezInfectious Diseases Department, Instituto Mexicano del Seguro Social, Hospital de Infectología, "La Raza" National Medical Center, IMSS, Seris y Jacarandas s/n, colonia la raza, Del Azcapotzalco, PO. 02990, Mexico City, Mexico.
Itzel Cruz-GrajalesInternal Medicine Department, Hospital General, "La Raza" National Medical Center, IMSS, Mexico City, Mexico.
Javier Enrique Cruz-HerreraInternal Medicine Department, Hospital HGZ-# 3, Querétaro, Mexico.
Luis Antonio Uribe-NoguezInfectious Diseases Department, Instituto Mexicano del Seguro Social, Hospital de Infectología, "La Raza" National Medical Center, IMSS, Seris y Jacarandas s/n, colonia la raza, Del Azcapotzalco, PO. 02990, Mexico City, Mexico.
Jesus E Gaytán-MartínezInfectious Diseases Department, Instituto Mexicano del Seguro Social, Hospital de Infectología, "La Raza" National Medical Center, IMSS, Seris y Jacarandas s/n, colonia la raza, Del Azcapotzalco, PO. 02990, Mexico City, Mexico.
Medardo Jerónimo-MoralesInternal Medicine Department, Hospital General, "La Raza" National Medical Center, IMSS, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study was to determine and compare the prevalences of polypharmacy and comorbidities in patients aged 50 years or older with those patients younger than 50 years in a Mexican population.

resultsOne hundred and twenty-five patients were enrolled, 60 (48%) were aged 50 years or older. The median CD4+ cell counts were 509 cells/μL (interquartile range [IQR]: 324-730) for the older patients and 384 cells/μL (IQR: 262-562) (P = 0.021) for the younger patients. Viral suppression were significantly higher in the older group: 80% vs. 63% (P = 0.037). The number of comorbidities was significantly higher in the older group, with a median of 2 (IQR: 2-3) vs. 1 (IQR: 0-1) (P ≤ 0.001). After adjustment of the logistic regression model in the older group, the following comorbidities differed between the age groups: systemic arterial hypertension (odds ratio [OR]: 15.75; 95% confidence interval [CI] 3.49-71.05; P = < 0.001), diabetes mellitus (OR: 14.36; 95% CI 1.79-115.07; P = 0.001), osteoarthritis (OR: 10.33; 95% CI 2.88-37.05; P = < 0.001), hyperlipidemia (OR: 2.78; 95% CI 1.22-6.34; P = 0.001), and polypharmacy (OR: 6.58; 95% CI 3.01-14.39; P = 0.001).

Indexed as

ComorbidityPolypharmacyAdultCase-Control StudiesHIV SeropositivityHumansMiddle AgedPrevalenceComorbidityHIVPolypharmacy

Identifiers

PMID31481133
PMCPMC6720088

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.