Evidence map›Paper›PMID 31481128›Full record

ArticleBMC complementary and alternative medicine2019

Inhibitory effect of purple rice husk extract on AFB

Arpamas Chariyakornkul, Charatda Punvittayagul, Sirinya Taya, Rawiwan Wongpoomchai

Open access · goldAbstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  3. International journal of molecular sciences · 2023
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  5. Review
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  7. Antioxidant Extract fromMolecules (Basel, Switzerland) · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Arpamas ChariyakornkulDepartment of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.
Charatda PunvittayagulResearch Affairs, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai, 50100, Thailand.
Sirinya TayaFunctional Food Research Unit, Science and Technology Research Institute, Chiang Mai University, Chiang Mai, 50200, Thailand.
Rawiwan WongpoomchaiDepartment of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand. rawiwan.wong@cmu.ac.th.ORCID http://orcid.org/0000-0001-6999-8436
Chiang Mai University · TH

Funding

Graduate Student Supportive Fund, Faculty of Medicine, Chiang Mai University 2558-2561National Research Council of Thailand 2016/218666
6 · The paper itself

Abstract

backgroundRice husk, a waste material produced during milling, contains numerous phytochemicals that may be sources of cancer chemopreventive agents. Various biological activities of white and colored rice husk have been reported. However, there are few comparative studies of the cancer chemopreventive effects of white and colored rice husk.

methodsThis study investigated the cancer chemopreventive activities of two different colors of rice husk using in vitro and in vivo models. A bacterial mutation assay using Salmonella typhimurium strains TA98 and TA100 was performed; enzyme induction activity in murine hepatoma cells was measured, and a liver micronucleus test was performed in male Wistar rats.

resultsThe white rice husk (WRHE) and purple rice husk (PRHE) extracts were not mutagenic in Salmonella typhimurium TA98 or TA100 in the presence or absence of metabolic activation. However, the extracts exhibited antimutagenicity against aflatoxin B

conclusionsPRHE showed potent cancer chemopreventive activity in a rat liver micronucleus assay through modulation of phase I and II xenobiotic metabolizing enzymes involved in AFB

Indexed as

Aflatoxin B1AnimalsAntimutagenic AgentsCell LineInactivation, MetabolicLiverMaleMicronuclei, Chromosome-DefectiveMicronucleus TestsOryzaPlant ExtractsRatsRats, WistarSalmonella typhimuriumAflatoxin B1Antimutagenic AgentsPlant ExtractsAflatoxin B1Liver micronucleus testMutagenicityRice huskXenobiotic metabolizing enzymes

Identifiers

PMID31481128
PMCPMC6724366
OpenAlexW2972013934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.