Evidence map›Paper›PMID 31481052›Full record

ArticleBMC complementary and alternative medicine2019

In vivo assessment of anticoagulant and antiplatelet effects of Syzygium cumini leaves extract in rabbits.

Ahad Abdul Rehman, Azra Riaz, Muhammad Arif Asghar, Muhammad Liaquat Raza, Shadab Ahmed, Kamran Khan

Open access · goldAbstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 27 citations in OpenAlex.

  1. Frontiers in pharmacology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ahad Abdul RehmanDepartment of Pharmacology, Faculty of Pharmacy, Jinnah Sindh Medical University, Rafiqui H.J Shaheed Road, Karachi, 75510, Pakistan.
Azra RiazDepartment of Pharmacology, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan.
Muhammad Arif AsgharDepartment of Pharmaceutics, Faculty of Pharmacy, Jinnah Sindh Medical University, Rafiqui H.J Shaheed Road, Karachi, 75510, Pakistan. m.arifasgher@hotmail.com.ORCID http://orcid.org/0000-0002-3220-8418
Muhammad Liaquat RazaDepartment of Clinical Sciences, Faculty of Medicine, Lund University Hospital, Lund, Sweden.
Shadab AhmedDepartment of Pharmacology, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan.
Kamran KhanDepartment of Pharmaceutics, Faculty of Pharmacy, Jinnah Sindh Medical University, Rafiqui H.J Shaheed Road, Karachi, 75510, Pakistan.
Jinnah Sindh Medical University · PKUniversity of Karachi · PKLund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSyzygium cumini (L.) Skeels. is one of the very popular traditionally used medicinal plants with numerous pharmacological activities including antioxidant, hypoglycemic and anti-inflammatory. However, actions of S. cumini on blood coagulation and other parameters of blood were poorly pharmacologically studied. Therefore, aim of this present investigation is to examine the effects of methanolic extract of S. cumini on blood coagulation and anticoagulation factors in healthy white albino rabbits at different doses.

methodsBlood samples were drawn twice during this study and biochemical assays were performed to determine the effect on different parameters such as coagulation, anticoagulation, hematological, Protein C (PC) and thrombin antithrombin (TAT) complex and platelet aggregation.

resultsThe results showed significant increase in RBCs, hemoglobin, hematocrit and platelets counts up to 1.4 × 10

conclusionThe obtained findings of hematological and coagulation tests concludes possibly S. cumini possess anticoagulant and antiplatelet effects.

Indexed as

AnimalsAnticoagulantsBlood CoagulationMalePlant ExtractsPlant LeavesPlatelet AggregationPlatelet Aggregation InhibitorsRabbitsSyzygiumAnticoagulantsPlant ExtractsPlatelet Aggregation InhibitorsCoagulationPlateletsProthrombinSyzygium cuminiThrombin

Identifiers

PMID31481052
PMCPMC6724265
OpenAlexW2972204477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.