Evidence map›Paper›PMID 31480885›Full record

ArticleOrganogenesis2019

Specification of Sprouty2 functions in osteogenesis in

Barbora Vesela, Eva Svandova, Maria Hovorakova, Renata Peterkova, Adela Kratochvilova, Martina Pasovska, Alice Ramesova, Herve Lesot, Eva Matalova

Open access · bronzeAbstract read
In one paragraph

Article in Organogenesis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. AnStem cells international · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Barbora VeselaLaboratory of Odontogenesis and Osteogenesis, Institute of Animal Physiology and Genetics, Academy of Sciences , Brno , Czech Republic.
Eva SvandovaLaboratory of Odontogenesis and Osteogenesis, Institute of Animal Physiology and Genetics, Academy of Sciences , Brno , Czech Republic.
Maria HovorakovaDepartment of Developmental Biology, Institute of Experimental Medicine, Czech Academy of Sciences , Prague , Czech Republic.ORCID 0000-0002-6346-6671
Renata PeterkovaDepartment of Histology and Embryology, Third Faculty of Medicine, Charles University , Prague , Czech Republic.ORCID 0000-0003-1454-2532
Adela KratochvilovaLaboratory of Odontogenesis and Osteogenesis, Institute of Animal Physiology and Genetics, Academy of Sciences , Brno , Czech Republic.
Martina PasovskaDepartment of Developmental Biology, Institute of Experimental Medicine, Czech Academy of Sciences , Prague , Czech Republic.
Alice RamesovaDepartment of Physiology, University of Veterinary and Pharmaceutical Sciences , Brno , Czech Republic.
Herve LesotLaboratory of Odontogenesis and Osteogenesis, Institute of Animal Physiology and Genetics, Academy of Sciences , Brno , Czech Republic.
Eva MatalovaLaboratory of Odontogenesis and Osteogenesis, Institute of Animal Physiology and Genetics, Academy of Sciences , Brno , Czech Republic.
Czech Academy of Sciences, Institute of Animal Physiology and Genetics · CZCharles University · CZUniversity of Veterinary Sciences Brno · CZCzech Academy of Sciences, Institute of Experimental Medicine · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sprouty proteins are modulators of the MAPK/ERK pathway. Amongst these, Sprouty2 (SPRY2) has been investigated as a possible factor that takes part in the initial phases of osteogenesis. However, the

Indexed as

Gene Expression Regulation, DevelopmentalOsteogenesisAnimalsBone DevelopmentCell DifferentiationCell ProliferationCytoplasmHypoxia-Inducible Factor 1, alpha SubunitMembrane ProteinsMiceMice, Inbred ICRMice, KnockoutOsteoblastsOsteoclastsOsteocytesOsteoprotegerinHif1a protein, mouseHypoxia-Inducible Factor 1, alpha SubunitMembrane ProteinsOsteoprotegerinProtein Serine-Threonine KinasesRANK LigandSpry2 protein, mouseTnfrsf11b protein, mouseTnfsf11 protein, mouseEndochondral bone developmentgrowth platemouseossificationSPROUTY2

Identifiers

PMID31480885
PMCPMC6804697
OpenAlexW2972066882

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.