Evidence map›Paper›PMID 31480842›Full record

ArticleJournal of the American Chemical Society2019

Catalytic Deuterium Incorporation within Metabolically Stable β-Amino C-H Bonds of Drug Molecules.

Yejin Chang, Ahmet Yesilcimen, Min Cao, Yuyang Zhang, Bochao Zhang, Jessica Z Chan, Masayuki Wasa

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. B(COrganic letters · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Chemical Tagging ofJournal of the American Chemical Society · 2025
    Article
  6. Article
  7. Review
  8. B(CACS catalysis · 2024
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Asian journal of organic chemistry · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Consecutive β,β'-Selective C(spAngewandte Chemie (International ed. in English) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yejin ChangDepartment of Chemistry, Merkert Chemistry Center , Boston College , Chestnut Hill , Massachusetts 02467 , United States.
Ahmet YesilcimenDepartment of Chemistry, Merkert Chemistry Center , Boston College , Chestnut Hill , Massachusetts 02467 , United States.
Min CaoDepartment of Chemistry, Merkert Chemistry Center , Boston College , Chestnut Hill , Massachusetts 02467 , United States.
Yuyang ZhangDepartment of Chemistry, Merkert Chemistry Center , Boston College , Chestnut Hill , Massachusetts 02467 , United States.
Bochao ZhangDepartment of Chemistry, Merkert Chemistry Center , Boston College , Chestnut Hill , Massachusetts 02467 , United States.
Jessica Z ChanDepartment of Chemistry, Merkert Chemistry Center , Boston College , Chestnut Hill , Massachusetts 02467 , United States.
Masayuki WasaDepartment of Chemistry, Merkert Chemistry Center , Boston College , Chestnut Hill , Massachusetts 02467 , United States.ORCID 0000-0002-3309-9129

Funding

Catalytic and Stereoselective C-C-Heteroatom Bond Forming ReactionsR35GM128695 · NIGMS · UNIVERSITY OF FLORIDA · PI Masayuki Wasa · 2018 to 2026
$3.8M
NIGMS NIH HHS R35 GM128695
6 · The paper itself

Abstract

An efficient deuteration process of β-amino C-H bonds in various

Indexed as

AminesCatalysisDeuteriumPharmaceutical PreparationsAminesDeuteriumPharmaceutical Preparations

Identifiers

PMID31480842
PMCPMC7123439

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.