Evidence map›Paper›PMID 31480789›Full record

ArticleMolecules (Basel, Switzerland)2019

Fungicide Tebuconazole Influences the Structure of Human Serum Albumin Molecule.

Katarína Želonková, Samuel Havadej, Valéria Verebová, Beáta Holečková, Jozef Uličný, Jana Staničová

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Katarína ŽelonkováFaculty of Science, Pavol Jozef Šafárik University, Jesenná 5, 041 54 Košice, Slovakia.
Samuel HavadejFaculty of Science, Pavol Jozef Šafárik University, Jesenná 5, 041 54 Košice, Slovakia. samuel.havadej@student.upjs.sk.
Valéria VerebováDepartment of Chemistry, Biochemistry & Biophysics, University of Veterinary Medicine & Pharmacy, Komenského 73, 041 81 Košice, Slovakia. valeria.verebova@uvlf.sk.
Beáta HolečkováDepartment of Biology & Genetics, University of Veterinary Medicine & Pharmacy, Komenského 73, 041 81 Košice, Slovakia. beata.holeckova@uvlf.sk.
Jozef UličnýFaculty of Science, Pavol Jozef Šafárik University, Jesenná 5, 041 54 Košice, Slovakia. jozef.ulicny@upjs.sk.ORCID 0000-0003-2853-8227
Jana StaničováDepartment of Chemistry, Biochemistry & Biophysics, University of Veterinary Medicine & Pharmacy, Komenského 73, 041 81 Košice, Slovakia. jana.stanicova@uvlf.sk.
University of Pavol Jozef Šafárik · SKUniversity of Veterinary Medicine in Košice · SKCharles University · CZ

Funding

Ministerstvo školstva, vedy, výskumu a športu Slovenskej republiky MediPark, Košice - Phase II, ITMS2014+ 313011, VEGA No. 1/0242/19 and KEGA No. 012 UVLF - 4/2018
6 · The paper itself

Abstract

Studies of interactions between pesticides and target mammalian proteins are important steps toward understanding the pesticide's toxicity. Using calorimetric and spectroscopic methods, the interaction between triazole fungicide tebuconazole and human serum albumin has been investigated. The spectroscopic techniques showed that fluorescence quenching of human serum albumin by tebuconazole was the result of the formation of tebuconazole/human serum albumin complex with the static type as the dominant mechanism. The association constant was found to be 8.51 × 10

Indexed as

Calorimetry, Differential ScanningFungicides, IndustrialHumansIbuprofenKetoprofenMolecular Docking SimulationProtein BindingSerum Albumin, HumanSpectrometry, FluorescenceThermodynamicsTriazolesFungicides, IndustrialIbuprofenKetoprofenSerum Albumin, HumantebuconazoleTriazoleshuman serum albumininteractionmolecular modelingspectroscopytebuconazole

Identifiers

PMID31480789
PMCPMC6749206
OpenAlexW2972122158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.