Evidence map›Paper›PMID 31480762›Full record

ArticleMolecules (Basel, Switzerland)2019

Comparison of the Utility of RP-TLC Technique and Different Computational Methods to Assess the Lipophilicity of Selected Antiparasitic, Antihypertensive, and Anti-inflammatory Drugs.

Alina Pyka-Pająk, Wioletta Parys, Małgorzata Dołowy

Abstract readComparative Study
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alina Pyka-PająkDepartment of Analytical Chemistry, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, PL-4 Jagiellońska Street, 41-200 Sosnowiec, Poland. apyka@sum.edu.pl.
Wioletta ParysDepartment of Analytical Chemistry, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, PL-4 Jagiellońska Street, 41-200 Sosnowiec, Poland. wparys@sum.edu.pl.
Małgorzata DołowyDepartment of Analytical Chemistry, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, PL-4 Jagiellońska Street, 41-200 Sosnowiec, Poland.

Funding

Medical University of Silesia KNW-1-057/K/8/O
6 · The paper itself

Abstract

The aim of this study was to assess the lipophilicity of selected antiparasitic, antihypertensive and non-steroidal anti-inflammatory drugs (NSAIDs) by means of reversed phase-thin layer chromatography (RP-TLC) as well by using Soczewiński-Wachtmeister's and J. Ościk's equations. The lipophilicity parameters of all examined compounds obtained under various chromatographic systems (i.e., methanol-water and acetone-water, respectively) and those determined on the basis of Soczewiński-Wachtmeister's and Ościk's equations (i.e., R

Indexed as

Antihypertensive AgentsAnti-Inflammatory AgentsAntiparasitic AgentsChromatography, Reverse-PhaseChromatography, Thin LayerLipidsAntihypertensive AgentsAnti-Inflammatory AgentsAntiparasitic AgentsLipidsantihypertensive drugsanti-inflammatory drugsantiparasitic drugslipophilicityOścik’s equationSoczewiński–Wachtmeister’s equation

Identifiers

PMID31480762
PMCPMC6749294

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.