ReviewCancers2019
Cutaneous Metastases in Ovarian Cancer.
Review in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 32 citations in OpenAlex.
- Management of skin metastases of ovarian cancer: a novel therapeutic approach.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Article
- Erythematous Nodules and Plaques on the Neck: A Quiz.Acta dermato-venereologica · 2026Article
- When dermoscopy of a nodule on the hysterectomy scar reveals peritoneal carcinomatosis from high-grade serous tubal carcinoma.Oxford medical case reports · 2026Article
- Clinicopathological Status and Prognostic Factors of Recurrent Epithelial Ovarian Cancer in Japan: Retrospective Survey of JSOG Committee on Gynecologic Oncology.The journal of obstetrics and gynaecology research · 2026Article
- An Update on Cutaneous Metastases of Internal Malignancies.Medicina (Kaunas, Lithuania) · 2025Review
- Cutaneous Metastases-Histological Particularities of Multifaceted Entities.Dermatopathology (Basel, Switzerland) · 2025Article
- Skin Metastasis from Cervical Adenocarcinoma with Intrapulmonary Metastasis and Metachronous Ovarian Cancer Responding to Chemotherapy: A Case Report and Review.Cancer management and research · 2025Article
- Skin metastasis from ovarian cancer with somatic BRCA1 mutation: A case report and literature review.Oncology letters · 2024Article
- Abdominal Parietal Metastasis from Cervical Cancer: A Review of One of the Most Uncommon Sites of Recurrence Including a Report of a New Case.Life (Basel, Switzerland) · 2024Review
- Radiation Therapy for Sister Mary Joseph's Nodule: A Review.Advances in radiation oncology · 2024Review
- Dermoscopy of skin metastases in advanced cancer-systemic (visceral, hematologic) and cutaneous.Frontiers in medicine · 2024Article
- Long-term survival of the Sister Mary Joseph nodule originating from breast cancer: A case report.World journal of clinical cases · 2023Article
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- Metastasis of ovarian cancer to nasal skin and skin on the trunk: a rare case report.Frontiers in oncology · 2023Article
- Cutaneous metastasis of carcinomatous component of ovarian carcinosarcoma: A case report and review of the literature.Diagnostic pathology · 2022Review
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- Cutaneous metastasis of PD-L1 positive ovarian carcinoma.Gynecologic oncology reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Skin metastases in ovarian cancer are uncommon, but their incidence may be increasing due to improved survival rates. Skin metastases can be divided into umbilical metastases, which are known as Sister Joseph nodules (SJNs) and are associated with peritoneal metastasis, and non-SJN skin metastases, which usually develop within surgical scars and in the vicinity of superficial lymphadenopathy. As most skin metastases develop after specific conditions, recognition of preceding metastatic diseases and prior treatments is necessary for early diagnosis of skin lesions. The prognosis of skin metastases in ovarian cancer varies widely since they are heterogeneous in the site of lesion and the time of appearance. Patients with SJNs at initial diagnosis and patients with surgical scar recurrences without concomitant metastases may have prolonged survival with a combination of surgery and chemotherapy. In patients who developed skin recurrences as a late manifestation, symptoms should be treated with external beam radiotherapy and immune response modifiers. Immune checkpoint blockade can enhance anti-tumor immunity and induce durable clinical responses in multiple tumor types, including advanced chemoresistant ovarian cancer. With the use of radiation therapy, which enhances the systemic anti-tumor immune response, immune checkpoint blockade may be a promising therapeutic strategy for distant metastasis, including skin metastasis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.