ReviewPolymers2019
Bone Repair and Regenerative Biomaterials: Towards Recapitulating the Microenvironment.
Review in Polymers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 72 citations in OpenAlex.
- Electrospun PPDO-BG/PVDF fibrous membranes with piezoelectric synergistic bioactive ion controlled release for enhanced bone repair.Regenerative biomaterials · 2026Article
- Promotion of Bone Defect Repair Using Decellularized Antler Cancellous Bone Loaded with Deer Osteoglycin.Biomolecules · 2025Article
- Assessment of the Osseointegration of Pure-Phase β-Tricalcium Phosphate (β-TCP) Ceramic Cylinder Implants in Critical Segmental Radial Bone Defects in Rabbits.Veterinary sciences · 2025Article
- In Situ Preparation of Composite Scaffolds Based on Polyurethane and Hydroxyapatite Particles for Bone Tissue Engineering.ACS omega · 2025Article
- Emerging Strategies for Bioactive Agent-Loaded Xenogeneic Bone Scaffolds in Regenerative Medicine: A Comprehensive Review.Drug design, development and therapy · 2025Review
- Advances in Bioceramics for Bone Regeneration: A Narrative Review.Biomimetics (Basel, Switzerland) · 2024Review
- ROS Scavenging and Osteogenic Differentiation Potential of L-Methionine-Substituted Poly(Organophosphazene) Electrospun Fibers.Biomimetics (Basel, Switzerland) · 2024Article
- Development of Hybrid Implantable Local Release Systems Based on PLGA Nanoparticles with Applications in Bone Diseases.Polymers · 2024Article
- Novel Organic-Inorganic Nanocomposite Hybrids Based on Bioactive Glass Nanoparticles and Their Enhanced Osteoinductive Properties.Biomolecules · 2024Article
- Sol-Gel Derived Gelatin-Bioactive Glass Nanocomposite Biomaterials Incorporating Calcium Chloride and Calcium Ethoxide.Polymers · 2024Article
- Non-Woven Fibrous Polylactic Acid/Hydroxyapatite Nanocomposites Obtained via Solution Blow Spinning: Morphology, Thermal and Mechanical Behavior.Nanomaterials (Basel, Switzerland) · 2024Article
- Pioneering nanomedicine in orthopedic treatment care: a review of current research and practices.Frontiers in bioengineering and biotechnology · 2024Review
- A microfluidic organ-on-a-chip: into the next decade of bone tissue engineering applied in dentistry.Future science OA · 2023Review
- Article
- Osteoimmune Properties of Mesoporous Bioactive Nanospheres: A Study on T Helper Lymphocytes.Nanomaterials (Basel, Switzerland) · 2023Article
- Biodegradable Materials for Tissue Engineering: Development, Classification and Current Applications.Journal of functional biomaterials · 2023Review
- Ceramic Materials for Biomedical Applications: An Overview on Properties and Fabrication Processes.Journal of functional biomaterials · 2023Review
- Creating a Microenvironment to Give Wings to Dental Pulp Regeneration-Bioactive Scaffolds.Pharmaceutics · 2023Review
- Novel Approaches and Biomaterials for Bone Tissue Engineering: A Focus on Silk Fibroin.Materials (Basel, Switzerland) · 2022Review
- Bioactive fluorescent hybrid microparticles as a stand-alone osteogenic differentiation inducer.Materials today. Bio · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biomaterials and tissue engineering scaffolds play a central role to repair bone defects. Although ceramic derivatives have been historically used to repair bone, hybrid materials have emerged as viable alternatives. The rationale for hybrid bone biomaterials is to recapitulate the native bone composition to which these materials are intended to replace. In addition to the mechanical and dimensional stability, bone repair scaffolds are needed to provide suitable microenvironments for cells. Therefore, scaffolds serve more than a mere structural template suggesting a need for better and interactive biomaterials. In this review article, we aim to provide a summary of the current materials used in bone tissue engineering. Due to the ever-increasing scientific publications on this topic, this review cannot be exhaustive; however, we attempted to provide readers with the latest advance without being redundant. Furthermore, every attempt is made to ensure that seminal works and significant research findings are included, with minimal bias. After a concise review of crystalline calcium phosphates and non-crystalline bioactive glasses, the remaining sections of the manuscript are focused on organic-inorganic hybrid materials.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.