ArticleMaterials (Basel, Switzerland)2019
Construction of Complex Structures Containing Micro-Pits and Nano-Pits on the Surface of Titanium for Cytocompatibility Improvement.
Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Fine-Tuning the Nanostructured Titanium Oxide Surface for Selective Biological Response.ACS applied bio materials · 2023Article
- Fabrication of Antibacterial TiOACS omega · 2022Article
- Titanium Nanobowl-Based Nest-Like Nanofiber Structure Prepared at Room Temperature and Pressure Promotes Osseointegration of Beagle Implants.Frontiers in bioengineering and biotechnology · 2022Article
- Effect of microtopography on osseointegration of implantable biomaterials and its modification strategies.Frontiers in bioengineering and biotechnology · 2022Review
- Bio-Performance of Hydrothermally and Plasma-Treated Titanium: The New Generation of Vascular Stents.International journal of molecular sciences · 2021Article
- Nanoparticles and Nanostructured Surface Fabrication for Innovative Cranial and Maxillofacial Surgery.Materials (Basel, Switzerland) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The surface topography of medical implants plays an important role in the regulation of cellular responses. Microstructure and nanostructure surfaces have been proved to enhance cell spreading and proliferation with respect to smooth surfaces. In this study, we fabricated a new structure including micro-pits and nano-pits on the surface of titanium via sandblasting, acid etching and chemical oxidation to investigate the influence of composite structures on cell behavior. Meanwhile, the surface properties and corrosion resistance of treated samples were also tested. The micro/nanostructured titanium surface comprising of micro-pits and nano-pits presented enhanced roughness and hydrophilicity. In addition, the corrosion resistance of the titanium substrate with micro-pits and nano-pits was significantly improved compared to that of polished titanium. More importantly, the micro/nanostructured titanium surface proved a good interfacial environment to promote osteoblast functions such as cell adhesion and spreading. Taken together, these results showed that the construction of micro/nanostructure on the titanium surface is an effective modification strategy to improve osteoblast cell responses.
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Registered trials
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