Evidence map›Paper›PMID 31480687›Full record

ArticleMarine drugs2019

Characterization and Antibiofilm Activity of Mannitol-Chitosan-Blended Paste for Local Antibiotic Delivery System.

Leslie R Pace, Zoe L Harrison, Madison N Brown, Warren O Haggard, J Amber Jennings

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Drug delivery strategies for antibiofilm therapy.Nature reviews. Microbiology · 2023
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Staphylococcal infection prevention using antibiotic-loaded mannitol-chitosan paste in a rabbit model of implant-associated osteomyelitis.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Leslie R PaceDepartment of Biomedical Engineering, Herff College of Engineering, University of Memphis, Memphis, TN 38152, USA.
Zoe L HarrisonDepartment of Biomedical Engineering, Herff College of Engineering, University of Memphis, Memphis, TN 38152, USA.
Madison N BrownDepartment of Biomedical Engineering, Herff College of Engineering, University of Memphis, Memphis, TN 38152, USA.
Warren O HaggardDepartment of Biomedical Engineering, Herff College of Engineering, University of Memphis, Memphis, TN 38152, USA.
J Amber JenningsDepartment of Biomedical Engineering, Herff College of Engineering, University of Memphis, Memphis, TN 38152, USA. jjnnings@memphis.edu.ORCID 0000-0002-2760-6948
University of Memphis · US

Funding

Foundation for the National Institutes of Health R01AR066050
6 · The paper itself

Abstract

Mannitol, a polyalcohol bacterial metabolite, has been shown to activate dormant persister cells within bacterial biofilm. This study sought to evaluate an injectable blend of mannitol, chitosan, and polyethylene glycol for delivery of antibiotics and mannitol for eradication of

Indexed as

AmikacinAnti-Bacterial AgentsBiofilmsChitosanDrug CarriersDrug Delivery SystemsInflammationMannitolMicrobial Sensitivity TestsPolyethylene GlycolsStaphylococcus aureusVancomycinAmikacinAnti-Bacterial AgentsChitosanDrug CarriersMannitolPolyethylene GlycolsVancomycinbiofilmbiomaterialchitosanimplantinfectionlocal drug deliverymannitolpersisterStaphylococcus

Identifiers

PMID31480687
PMCPMC6780707
OpenAlexW2970507963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.