Evidence map›Paper›PMID 31480654›Full record

ArticleMaterials (Basel, Switzerland)2019

Antimicrobial Activity of Protamine-Loaded Calcium Phosphates against Oral Bacteria.

Masashi Fujiki, Kodai Abe, Tohru Hayakawa, Takatsugu Yamamoto, Mana Torii, Keishi Iohara, Daisuke Koizumi, Rie Togawa, Mamoru Aizawa, Michiyo Honda

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Masashi FujikiDepartment of Applied Chemistry, School of Science and Technology, Meiji University, 1-1-1, Higashimita, Tama-ku, Kawasaki 214-8571, Kanagawa, Japan.
Kodai AbeDepartment of Applied Chemistry, School of Science and Technology, Meiji University, 1-1-1, Higashimita, Tama-ku, Kawasaki 214-8571, Kanagawa, Japan.
Tohru HayakawaDepartment of Dental Engineering, Tsurumi University School of Dental Medicine, 2-1-3, Tsurumi, Tsurumi-ku, Yokohama 230-8501, Kanagawa, Japan.
Takatsugu YamamotoDepartment of Operative Dentistry, Tsurumi University School of Dental Medicine, 2-1-3, Tsurumi, Tsurumi-ku, Yokohama 230-8501, Kanagawa, Japan.
Mana ToriiDepartment of Removable Prosthodontics, Tsurumi University School of Dental Medicine, 2-1-3, Tsurumi, Tsurumi-ku, Yokohama 230-8501, Kanagawa, Japan.
Keishi IoharaCentral Research Institute, Maruha Nichiro Corporation, 16-2, Wadai, Tsukuba 300-4295, Ibaraki, Japan.
Daisuke KoizumiCentral Research Institute, Maruha Nichiro Corporation, 16-2, Wadai, Tsukuba 300-4295, Ibaraki, Japan.
Rie TogawaCentral Research Institute, Maruha Nichiro Corporation, 16-2, Wadai, Tsukuba 300-4295, Ibaraki, Japan.
Mamoru AizawaDepartment of Applied Chemistry, School of Science and Technology, Meiji University, 1-1-1, Higashimita, Tama-ku, Kawasaki 214-8571, Kanagawa, Japan.
Michiyo HondaDepartment of Applied Chemistry, School of Science and Technology, Meiji University, 1-1-1, Higashimita, Tama-ku, Kawasaki 214-8571, Kanagawa, Japan. michiyoh@meiji.ac.jp.
Meiji University · JPTsurumi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protamine is an antimicrobial peptide extracted from fish. In this study, we loaded protamine onto dicalcium phosphate anhydride (DCPA), a dental material. Protamine was loaded by stirring DCPA into a protamine solution. To explore the antimicrobial activity of the materials, we cultivated

Indexed as

antimicrobial peptidebiofilm formationdental materialdicalcium phosphate anhydrideprotamineStreptococcus mutans

Identifiers

PMID31480654
PMCPMC6747779
OpenAlexW2971151499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.