ArticleNutrients2019
Complications Associated with Enteral Nutrition: CAFANE Study.
Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- The Application and Mechanism Analysis of Enteral Nutrition in Clinical Management of Chronic Diseases.Nutrients · 2025Pooled it
- Clinical effects and safety of semi-solid feeds in tube-fed patients: a meta-analysis and systematic review.Frontiers in nutrition · 2024Pooled it
- The effects of dietary fiber on common complications in critically ill patients; with a special focus on viral infections; a systematic reveiw.Immunity, inflammation and disease · 2022Pooled it
- Quality of Life of Cancer Patients Receiving Enteral Nutrition: A Systematic Review of Randomized Controlled Trials.Nutrients · 2021Pooled it
- Nutritional outcomes associated with enteral versus parenteral nutritional support during intensive induction chemotherapy for acute myeloid leukemia.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Observational
- Long-Term Antibiotic-Driven Gut Microbiota Disruption Promotes ToxigenicInfection and drug resistance · 2026Article
- Impact of weight loss and disease progression on survival in ALS: insights from a multidisciplinary care center.Arquivos de neuro-psiquiatria · 2025Article
- Knowledge, attitudes, and behaviors of ICU nurses for enteral nutrition-related diarrhea management: a cross-sectional study.BMC nursing · 2025Article
- Gastrointestinal Bleeding Associated With Nasojejunal Tube Injury in a Patient With Septic Shock: A Case Report.Cureus · 2025Article
- Disadvantages of various methods of gastrointestinal feeding in patients admitted to the intensive care unit: A systematic review.Caspian journal of internal medicine · 2025Review
- Pediatric to adult transition care in neurogastroenterology and motility: A position paper from the American Neurogastroenterology and Motility Society and European Society of Neurogastroenterology and Motility.Neurogastroenterology and motility · 2024Review
- Article
- Feeding Intolerance in Critically Ill Patients with Enteral Nutrition: A Meta-Analysis and Systematic Review.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2024Review
- Standards for the Use of Enteral Nutrition in Patients with Diabetes or Stress Hyperglycaemia: Expert Consensus.Nutrients · 2023Article
- Article
- Examining the Nutrition, Oral Mucositis, and Gastrointestinal System Symptoms of Intensive Care Units Patients Receiving Enteral and Parenteral Nutrition.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023Article
- Impact of nutritional and educational support on home enteral nutrition.Journal of health, population, and nutrition · 2023Article
- Factors affecting target caloric achievement and calorie intake improvement: the nutrition support team's role.Frontiers in nutrition · 2023Article
- Chinese expert consensus on prevention and intervention for the elderly with malnutrition (2022).Aging medicine (Milton (N.S.W)) · 2022Article
- Blenderised Tube Feeds vs. Commercial Formula: Which Is Better for Gastrostomy-Fed Children?Nutrients · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesTo determine the association between home enteral nutrition (HEN) administration modality and its complications in patients.
methodsThis is a prospective multicenter longitudinal study including 15 Spanish hospitals, from April 2015 to March 2017. A 4-month follow-up period was conducted for each patient by home visit. The study subjects were adult patients who began their nutrient intake by tube feeding, known as HEN, during the recruitment period. The variables studied included the type and modality of HEN administration and its related complications, such as vomiting, regurgitation, constipation, diarrhea, and abdominal distention. Mechanical complications and bronchoaspiration were also evaluated. Descriptive variables were used for fitting.
resultsThe study consisted of 306 patients; 4 were lost due to death. Specific HEN modalities protected against constipation (odds ratio (OR) = 0.4) and regurgitation (OR = 0.4). The use of a nasogastric tube (NGT) resulted in a lower risk of diarrhea compared to percutaneous endoscopic gastrostomy (PEG) (OR = 0.4) but resulted in a higher risk of tube obstruction (OR = 7.4). The use of intermittent gravity versus bolus feeding was a protection factor against vomiting (OR = 0.4), regurgitation (OR = 0.3), constipation (OR = 0.3), diarrhea (OR = 0.4) and abdominal distension (OR = 0.4). The increase in the number of doses was a risk factor for the incidence of regurgitation (OR = 1.3).
conclusionsGastrointestinal complications were the most frequent problems, but an adequate choice of the formula, route, feeding modality, number of doses, administration time, and dose volume can reduce the risk of these complications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.