Evidence map›Paper›PMID 31480549›Full record

ArticleInternational journal of molecular sciences2019

Dynamic mRNA Expression Analysis of the Secondary Palatal Morphogenesis in Miniature Pigs.

Jia Liu, Jing Chen, Dong Yuan, Lindong Sun, Zhipeng Fan, Songlin Wang, Juan Du

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jia LiuDepartment of geriatric dentistry, Capital Medical University School of Stomatology, Tiantan Xili No. 4, Beijing 100050, China.
Jing ChenLaboratory of Molecular Signaling and Stem Cells Therapy, Molecular Laboratory for Gene Therapy and Tooth Regeneration, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, Capital Medical University School of Stomatology, Tiantan Xili No. 4, Beijing 100050, China.
Dong YuanDepartment of geriatric dentistry, Capital Medical University School of Stomatology, Tiantan Xili No. 4, Beijing 100050, China.
Lindong SunLaboratory of Molecular Signaling and Stem Cells Therapy, Molecular Laboratory for Gene Therapy and Tooth Regeneration, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, Capital Medical University School of Stomatology, Tiantan Xili No. 4, Beijing 100050, China.
Zhipeng FanLaboratory of Molecular Signaling and Stem Cells Therapy, Molecular Laboratory for Gene Therapy and Tooth Regeneration, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, Capital Medical University School of Stomatology, Tiantan Xili No. 4, Beijing 100050, China.
Songlin WangLaboratory of Molecular Signaling and Stem Cells Therapy, Molecular Laboratory for Gene Therapy and Tooth Regeneration, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, Capital Medical University School of Stomatology, Tiantan Xili No. 4, Beijing 100050, China.
Juan DuDepartment of geriatric dentistry, Capital Medical University School of Stomatology, Tiantan Xili No. 4, Beijing 100050, China. juandug@ccmu.edu.cn.
Capital Medical University · CN

Funding

Beijing Scholar Program PXM 2013_014226_000055, PXM2015_014226_000116, PXM2015_014226_000055, PXM2015_014226_000052High-Level Talents of the Beijing Health System 2014-3-077National Natural Science Foundation of China 81570940 and 81873706
6 · The paper itself

Abstract

Normal mammalian palatogenesis is a complex process that requires the occurrence of a tightly regulated series of specific and sequentially regulated cellular events. Cleft lip/palate (CLP), the most frequent craniofacial malformation birth defects, may occur if any of these events undergo abnormal interference. Such defects not only affect the patients, but also pose a financial risk for the families. In our recent study, the miniature pig was shown to be a valuable alternative large animal model for exploring human palate development by histology. However, few reports exist in the literature to document gene expression and function during swine palatogenesis. To better understand the genetic regulation of palate development, an mRNA expression profiling analysis was performed on miniature pigs,

Indexed as

MorphogenesisSignal TransductionTranscriptomeAnimalsGene Expression Regulation, DevelopmentalHedgehog ProteinsMAP Kinase Signaling SystemPalateSequence Analysis, RNASwineSwine, MiniatureWnt Signaling PathwayHedgehog Proteinscleft lip/palategene expression profileminiature pigpalate development

Identifiers

PMID31480549
PMCPMC6747431
OpenAlexW2971086615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.