Evidence map›Paper›PMID 31480538›Full record

ArticleMaterials (Basel, Switzerland)2019

Electrospinning of Fish Gelatin Solution Containing Citric Acid: An Environmentally Friendly Approach to Prepare Crosslinked Gelatin Fibers.

Anna Liguori, Jone Uranga, Silvia Panzavolta, Pedro Guerrero, Koro de la Caba, Maria Letizia Focarete

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Advances in cardiac tissue engineering and heart-on-a-chip.Journal of biomedical materials research. Part A · 2024
    Review
  5. Article
  6. Acellular fish skin for wound healing.International wound journal · 2023
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Electrospinning Live Cells Using Gelatin and Pullulan.Bioengineering (Basel, Switzerland) · 2020
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anna LiguoriDepartment of Chemistry "Giacomo Ciamician" and INSTM UdR of Bologna, University of Bologna, via Selmi 2, 40126 Bologna, Italy.
Jone UrangaBIOMAT research group, University of the Basque Country (UPV/EHU), Engineering College of Gipuzkoa, Plaza de Europa 1, 20018 Donostia-San Sebastián, Spain.
Silvia PanzavoltaDepartment of Chemistry "Giacomo Ciamician" and INSTM UdR of Bologna, University of Bologna, via Selmi 2, 40126 Bologna, Italy.
Pedro GuerreroBIOMAT research group, University of the Basque Country (UPV/EHU), Engineering College of Gipuzkoa, Plaza de Europa 1, 20018 Donostia-San Sebastián, Spain.ORCID 0000-0002-9785-7048
Koro de la CabaBIOMAT research group, University of the Basque Country (UPV/EHU), Engineering College of Gipuzkoa, Plaza de Europa 1, 20018 Donostia-San Sebastián, Spain. koro.delacaba@ehu.eus.ORCID 0000-0002-8866-7314
Maria Letizia FocareteDepartment of Chemistry "Giacomo Ciamician" and INSTM UdR of Bologna, University of Bologna, via Selmi 2, 40126 Bologna, Italy. marialetizia.focarete@unibo.it.ORCID 0000-0002-0458-7836

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The majority of the crosslinking approaches employed to confer water resistance properties to electrospun gelatin mats are based on the use of potential cytotoxic agents, turning out to be not suitable for biomedical applications. Environmentally friendly chemical strategies based on the use of non-toxic agents are, therefore, strongly demanded. In the present work, the possibility to produce crosslinked electrospun fish gelatin mats by electrospinning an aqueous solution, containing citric acid as a crosslinking agent, is reported. The effect of pH on solution rheological properties, as well as on the electrospun mat morphology, chemistry, and crosslinking degree, is assessed. The increase of solution pH from 1.8 to 3.7 allows for obtaining fibers that maintain the fibrous morphology also in the mat. Subsequent thermal treatment of the electrospun mat (80 °C for 30 min) turns out to increase the crosslinking degree and morphological stability of the mat.

Indexed as

citric acidcrosslinking degreeelectrospinningfish gelatingelatin structurepHthermal treatment

Identifiers

PMID31480538
PMCPMC6747780

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.