Evidence map›Paper›PMID 31480310›Full record

ArticleInternational journal of molecular sciences2019

Water-Soluble Fullerenol C

Chiang-Wen Lee, Miao-Ching Chi, Kuo-Ti Peng, Yao-Chang Chiang, Lee-Fen Hsu, Yi-Ling Yan, Hsing-Yen Li, Ming-Chun Chen, I-Ta Lee, Chian-Hui Lai

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Air Pollution and Skin Diseases.Annals of dermatology · 2025
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Fullerenol CInternational journal of nanomedicine · 2024
    Article
  10. Article
  11. Article
  12. The Effect of Fullerenol CInternational journal of molecular sciences · 2021
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Chiang-Wen LeeDepartment of Nursing, Division of Basic Medical Sciences, and Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology, Puzi City, Chiayi County 613, Taiwan.
Miao-Ching ChiDepartment of Nursing, Division of Basic Medical Sciences, and Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology, Puzi City, Chiayi County 613, Taiwan.
Kuo-Ti PengDepartment of Orthopaedic Surgery, Chang Gung Memorial Hospital, Puzi City, Chiayi County 613, Taiwan.
Yao-Chang ChiangDepartment of Nursing, Division of Basic Medical Sciences, and Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology, Puzi City, Chiayi County 613, Taiwan.ORCID 0000-0002-7619-1902
Lee-Fen HsuDepartment of Nursing, Division of Basic Medical Sciences, and Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology, Puzi City, Chiayi County 613, Taiwan.
Yi-Ling YanDepartment of Nursing, Division of Basic Medical Sciences, and Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology, Puzi City, Chiayi County 613, Taiwan.
Hsing-Yen LiGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung 402, Taiwan.
Ming-Chun ChenGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung 402, Taiwan.
I-Ta LeeSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan. itlee0128@tmu.edu.tw.
Chian-Hui LaiGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung 402, Taiwan. chianhuilai@dragon.nchu.edu.tw.ORCID 0000-0002-2697-4845
Chang Gung University of Science and Technology · TWKaohsiung Medical University · TWChang Gung University · TWNational Chung Hsing University · TWTaipei Medical University · TW

Funding

Chang Gung Medical Foundation CMRPF6G0081Ministry of Science and Technology, Taiwan 106-2320-B-255 -001 -, 107-2113-M-005 -014 -, 108-2113-M-005 -004 -
6 · The paper itself

Abstract

Particulate matter (PM), a widespread air pollutant, consists of a complex mixture of solid and liquid particles suspended in air. Many diseases have been linked to PM exposure, which induces an imbalance in reactive oxygen species (ROS) generated in cells, and might result in skin diseases (such as aging and atopic dermatitis). New techniques involving nanomedicine and nano-delivery systems are being rapidly developed in the medicinal field. Fullerene, a kind of nanomaterial, acts as a super radical scavenger. Lower water solubility levels limit the bio-applications of fullerene. Hence, to improve the water solubility of fullerene, while retaining its radical scavenger functions, a fullerene derivative, fullerenol C

Indexed as

Air PollutionApoptosisCell LineCitiesFilaggrin ProteinsFullerenesHumansInflammationKeratinocytesMitochondriaMitogen-Activated Protein KinasesModels, BiologicalParticulate MatterPhosphorylationProto-Oncogene Proteins c-aktReactive Oxygen SpeciesFilaggrin ProteinsFLG protein, humanFullerenesfullerenolMitogen-Activated Protein KinasesParticulate MatterProto-Oncogene Proteins c-aktReactive Oxygen SpeciesWateranti-inflammationantioxidantfullerenolhuman keratinocyte cellparticulate matterreactive oxygen species

Identifiers

PMID31480310
PMCPMC6747515
OpenAlexW2971237324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.