Evidence map›Paper›PMID 31480141›Full record

ArticleAsian-Australasian journal of animal sciences2019

Application of single-step genomic evaluation using social genetic effect model for growth in pig.

Joon Ki Hong, Young Sin Kim, Kyu Ho Cho, Deuk Hwan Lee, Ye Jin Min, Eun Seok Cho

Abstract read
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Article in Asian-Australasian journal of animal sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Joon Ki HongNational Institute of Animal Science, Rural Development Administration, Cheonan 31000, Korea.
Young Sin KimNational Institute of Animal Science, Rural Development Administration, Cheonan 31000, Korea.
Kyu Ho ChoNational Institute of Animal Science, Rural Development Administration, Cheonan 31000, Korea.
Deuk Hwan LeeDepartment of Animal Life Resources, Hankyong University, Anseong 17579, Korea.
Ye Jin MinNational Institute of Animal Science, Rural Development Administration, Cheonan 31000, Korea.
Eun Seok ChoNational Institute of Animal Science, Rural Development Administration, Cheonan 31000, Korea.

Funding

Rural Development Administration PJ01263601Rural Development Administration PJ01428902
6 · The paper itself

Abstract

objectiveSocial genetic effects (SGE) are an important genetic component for growth, group productivity, and welfare in pigs. The present study was conducted to evaluate i) the feasibility of the single-step genomic best linear unbiased prediction (ssGBLUP) approach with the inclusion of SGE in the model in pigs, and ii) the changes in the contribution of heritable SGE to the phenotypic variance with different scaling ω constants for genomic relationships.

methodsThe dataset included performance tested growth rate records (average daily gain) from 13,166 and 21,762 pigs Landrace (LR) and Yorkshire (YS), respectively. A total of 1,041 (LR) and 964 (YS) pigs were genotyped using the Illumina PorcineSNP60 v2 BeadChip panel. With the BLUPF90 software package, genetic parameters were estimated using a modified animal model for competitive traits. Giving a fixed weight to pedigree relationships (τ: 1), several weights (ωxx, 0.1 to 1.0; with a 0.1 interval) were scaled with the genomic relationship for best model fit with Akaike information criterion (AIC).

resultsThe genetic variances and total heritability estimates (T2) were mostly higher with ssGBLUP than in the pedigree-based analysis. The model AIC value increased with any level of ω other than 0.6 and 0.5 in LR and YS, respectively, indicating the worse fit of those models. The theoretical accuracies of direct and social breeding value were increased by decreasing ω in both breeds, indicating the better accuracy of ω0.1 models. Therefore, the optimal values of ω to minimize AIC and to increase theoretical accuracy were 0.6 in LR and 0.5 in YS.

conclusionIn conclusion, single-step ssGBLUP model fitting SGE showed significant improvement in accuracy compared with the pedigree-based analysis method; therefore, it could be implemented in a pig population for genomic selection based on SGE, especially in South Korean populations, with appropriate further adjustment of tuning parameters for relationship matrices.

Indexed as

AccuracyBreeding ValueLandraceSingle-step Genomic Best Linear Unbiased Prediction (BLUP)Social Genetic EffectsYorkshire

Identifiers

PMID31480141
PMCPMC6819686

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