Evidence map›Paper›PMID 31479914›Full record

ArticleResearch in developmental disabilities2019

Relations between caregiver-report of sleep and executive function problems in children with autism spectrum disorder and attention-deficit/hyperactivity disorder.

Amanda Cremone-Caira, Julia Buirkle, Rachel Gilbert, Nikita Nayudu, Susan Faja

Open access · greenAbstract read
In one paragraph

Article in Research in developmental disabilities, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Amanda Cremone-CairaDivision of Developmental Medicine, Boston Children's Hospital, 02215, United States; Harvard Medical School, 02215, United States.
Julia BuirkleUniversity of Massachusetts Medical School, 01655, United States.
Rachel GilbertDivision of Developmental Medicine, Boston Children's Hospital, 02215, United States.
Nikita NayuduChiltern International, 27513, United States.
Susan FajaDivision of Developmental Medicine, Boston Children's Hospital, 02215, United States; Harvard Medical School, 02215, United States. Electronic address: susan.faja@childrens.harvard.edu.
Boston Children's Hospital · USUniversity of Massachusetts Chan Medical School · US

Funding

Electrophysiological Response to Executive Control Training in AutismR00HD071966 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI FAJA, SUSAN · 2014 to 2016
$718k
Electrophysiological Response to Executive Control Training in AutismK99HD071966 · NICHD · UNIVERSITY OF WASHINGTON · PI FAJA, SUSAN · 2012 to 2013
$179k
NICHD NIH HHS K99 HD071966NICHD NIH HHS R00 HD071966
6 · The paper itself

Abstract

backgroundMany children with autism spectrum disorder (ASD) experience comorbid symptoms of attention-deficit/hyperactivity disorder (ADHD). Additionally, children with ASD and ADHD often have sleep disturbances and deficits in executive functioning (EF). In typical development, sleep disturbances are causally linked to EF deficits and exacerbate ADHD-like symptoms.

aimThe aim of this study was to determine whether caregiver-report sleep and EF difficulties predict ADHD symptoms in children with ASD.

methodsCaregiver-report of child sleep, EF, and ADHD symptom severity was collected for 101 children with ASD, 7-11 years of age. Hierarchical linear regressions tested the independent and interactive effects of sleep and EF in predicting ADHD symptoms.

resultsChildren with ASD were more likely to have symptoms of ADHD if they experienced both sleep and EF difficulties. Children with difficulties in working memory were particularly at risk for clinically significant symptoms of ADHD. Notably, however, sleep did not mediate or moderate the relation between working memory and ADHD symptoms in this sample, suggesting that these variables act through independent mechanisms to increase vulnerability for comorbidity.

conclusionsThese results have clinical significance as sleep and EF deficits may identify an ASD subgroup that is at increased risk for a comorbid ADHD diagnosis.

Indexed as

Attention Deficit Disorder with HyperactivityAutism Spectrum DisorderExecutive FunctionMemory DisordersSleep Wake DisordersBehavioral SymptomsCaregiversChildComorbidityFemaleHumansMaleMemory and Learning TestsMemory, Short-TermRisk FactorsSymptom AssessmentCognitive functioningDevelopmental disordersDevelopmental psychopathology

Identifiers

PMID31479914
PMCPMC6778038
OpenAlexW2971046485

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.