ArticlePLoS neglected tropical diseases2019
Leprosy in elderly people and the profile of a retrospective cohort in an endemic region of the Brazilian Amazon.
Article in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 31 citations in OpenAlex.
- Associated Factors of Mycobacterium Leprae Infection among People with Leprosy in Kwale County.PLoS neglected tropical diseases · 2025Article
- Determinants of leprosy among patients visiting Sheshamane comprehensive specialized hospital, West Arsi zone, oromia region, ethiopia: a case-control study.Scientific reports · 2025Article
- Ecuador Towards Zero Leprosy: A Twenty-Three-Year Retrospective Epidemiologic and Spatiotemporal Analysis of Leprosy in Ecuador.Tropical medicine and infectious disease · 2024Article
- Clinicoepidemiologic profile of leprosy in geriatric population in post-elimination era: A retrospective, hospital-based, cross-sectional study from Eastern India.Journal of family medicine and primary care · 2023Article
- The efficacy of a whole foods, plant-based dietary lifestyle intervention for the treatment of peripheral neuropathic pain in leprosy: a randomized control trial protocol.Frontiers in nutrition · 2023Article
- Clinical and radiological evaluation of maxillofacial and otorhinolaryngological manifestations of Hansen's disease.Scientific reports · 2022Article
- Chromoblastomycosis-Leprosy Co-Infection in Central West Brazil. Presentation of Three Cases and Literature Review.Mycopathologia · 2022Review
- Are the clinical features of leprosy and American tegumentary leishmaniasis worse in patients with both diseases?Revista do Instituto de Medicina Tropical de Sao Paulo · 2022Article
- Inequality of gender, age and disabilities due to leprosy and trends in a hyperendemic metropolis: Evidence from an eleven-year time series study in Central-West Brazil.PLoS neglected tropical diseases · 2021Article
- Evaluation of proposed cranial and maxillary bone alteration parameters in persons affected by Hansen's disease.PLoS neglected tropical diseases · 2021Article
- Presence of Senescent and Memory CD8+ Leukocytes as Immunocenescence Markers in Skin Lesions of Elderly Leprosy Patients.Frontiers in immunology · 2021Article
- Trends and forecasts of leprosy for a hyperendemic city from Brazil's northeast: Evidence from an eleven-year time-series analysis.PloS one · 2020Article
- Leprosy in Elderly and Children among New Cases - A 3-Year Retrospective Study.Indian dermatology online journalArticle
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7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLeprosy has a global presence; more than 180 thousand new cases were registered in 2013, 15% of which were found in the Americas. The elderly are a very susceptible demographic in terms of developing illnesses, mainly because of characteristics natural to the senescence of the human organism. This study's goals were to analyze leprosy in an elderly population from a hyperendemic region of the Brazilian Amazon in a historical series from 2004 to 2013 and to determine the clinical and epidemiological profile of a series of leprosy cases of elderly people in the period spanning from 2009 to 2013.
methodsTo achieve these goals, an observational, longitudinal, retrospective and descriptive study was put together to analyze leprosy in elderly people from data acquired from the Notification Aggravations Information System. Furthermore, a profile of the disease from a retrospective cohort based on data collected from medical records was developed.
resultsThe number of new cases and the leprosy detection rate decreased across the observed period but remained stable among the elderly. The trend for the next ten years indicates decreases in the number of cases and in the detection rate in the general population and an increase in only the elderly. The overall profile was characterized by a predominance of males (64.32%), the multibacillary clinical form (87.57%), Type 1 reaction episodes (37.50%) and some physical incapacity at diagnosis (49.19%). The risk of reaction was greater in the first six months of multidrug therapy, and the positive result from the skin smear was associated with the greater chance of reactional condition development.
conclusionsThe resulting data demonstrate that leprosy amongst the elderly deserves attention because of the increased susceptibility to disability in this age group, with their higher risk of reaction and their greater level of co-morbidity.
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