Evidence map›Paper›PMID 31479341›Full record

ArticleJournal of global oncology2019

Pathology Services in Nigeria: Cross-Sectional Survey Results From Three Cancer Consortia.

Peter Ntiamoah, Ngozi R Monu, Fatimah B Abdulkareem, Kayode A Adeniji, John O Obafunwa, Akinwumi O Komolafe, Clayton Yates, Ernest Kaninjing, John D Carpten, Bodour Salhia and 4 more

Abstract read
In one paragraph

Article in Journal of global oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Peter NtiamoahMemorial Sloan Kettering Cancer Center, New York, NY.
Ngozi R MonuWeill Cornell Medical College, New York, NY.
Fatimah B AbdulkareemUniversity of Lagos, Lagos, Nigeria.
Kayode A AdenijiUniversity of Ilorin Teaching Hospital, Ilorin, Nigeria.
John O ObafunwaLagos State University Teaching Hospital, Lagos, Nigeria.
Akinwumi O KomolafeObafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.
Clayton YatesTuskegee University, Tuskegee, AL.
Ernest KaninjingGeorgia College and State University, Milledgeville, GA.
John D CarptenUniversity of Southern California, Los Angeles, CA.
Bodour SalhiaUniversity of Southern California, Los Angeles, CA.
Folake T OdedinaUniversity of Florida Lake Nona Research and Academic Center, Orlando, FL.
Marcia EdelweissMemorial Sloan Kettering Cancer Center, New York, NY.
T Peter KinghamMemorial Sloan Kettering Cancer Center, New York, NY.
Olusegun I AlatiseObafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

purposeCancer incidence is increasing in sub-Saharan Africa, yet there is little information on the capacity of pathology laboratories in this region. We aimed to assess the current state of pathology services in Nigeria to guide strategies to ensure best practices and improve the quality of surgical specimen handling.

methodsWe developed structured pathology survey to assess tissue handling, sample processing, and immunohistochemistry (IHC) capabilities. The survey was distributed electronically to 22 medical centers in Nigeria that are part of established cancer consortia. Data were collected between September and October 2017.

resultsSixteen of 22 centers completed the survey in full. All 16 institutions had at least one board-certified pathologist and at least one full-time laboratory scientist/technologist. The majority of responding institutions (75%) reported processing fewer than 3,000 samples per year. For sample processing, 38% of institutions reported manual tissue processing and 75% processed biopsies and surgical specimens together. The average tissue fixation time ranged from 5 to more than 72 hours before processing and paraffin embedding. Half of the institutions reported having no quality assurance processes to evaluate hematoxylin and eosin-stained slides, and 25% reported having no written operating procedures. Half of the participating institutions have a facility for routine IHC staining, and among these there was considerable variability in processes and validation procedures. External proficiency testing was not common among surveyed sites (38%).

conclusionData from 16 Nigerian medical institutions indicate deficiencies in standardization, quality control, and IHC validation that could affect the reliability of pathology results. These findings highlight addressable gaps in pathology services that can ensure accurate diagnosis and follow-up for the growing number of patients with cancer in this region.

Indexed as

Cross-Sectional StudiesFemaleHumansIncidenceMaleNeoplasmsNigeriaSurveys and Questionnaires

Identifiers

PMID31479341
PMCPMC6733183

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.