Evidence map›Paper›PMID 31479005›Full record

Trial reportMedicine and science in sports and exercise2020

Skeletal Effects of Nine Months of Physical Activity in Obese and Healthy Weight Children.

Vineel Kondiboyina, Lauren B Raine, Arthur F Kramer, Naiman A Khan, Charles H Hillman, Sandra J Shefelbine

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Medicine and science in sports and exercise, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vineel KondiboyinaDepartment of Bioengineering, Northeastern University, Boston, MA.
Lauren B RaineDepartment of Psychology, Northeastern University, Boston, MA.
Arthur F Kramer
Naiman A KhanDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Champaign, IL.
Charles H Hillman
Sandra J Shefelbine

Funding

Enhancing Child Cognitive and Brain Health through Physical Activity TrainingR01HD069381 · NICHD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI MCAULEY, EDWARD · 2012 to 2016
$3.0M
ERPs to Academics: Exercise Effects on Cognition in School-Aged ChildrenR01HD055352 · NICHD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI HILLMAN, CHARLES H · 2008 to 2011
$1.3M
NICHD NIH HHS R01 HD055352NICHD NIH HHS R01 HD069381
6 · The paper itself

Abstract

purposeObesity during adolescence has multisystem health consequences. The objective of this work was to determine whether preadolescent overweight/obese children's bones respond to a 9-month physical activity intervention by increasing bone density similar to healthy weight children.

methodsParticipants included overweight/obese (BMI > 85%) and healthy weight (15% < BMI < 85%) preadolescents (8-9 yr old). Participants in the physical activity group participated in a 9-month physical activity curriculum every day after school. The wait list control group received no intervention. Both groups had overweight/obese children and healthy weight controls. Whole-body bone mineral content, area, and bone mineral apparent density (BMAD) were assessed using dual x-ray absorptiometry) at the beginning and end of the 9-month trial in the physical activity and control group.

resultsOverweight/obese preadolescent children had higher BMAD than healthy weight children (P < 0.001 for spine, leg, and whole body). However, the density/weight (BMAD/lean mass) was lower in overweight/obese children than that in healthy weight children, indicating that the density of bones in overweight/obese children may not compensate sufficiently for the excessive load due to weight. The change in BMAD over 9 months was greater in healthy weight children than overweight/obese children in the whole body and leg, but not the lumbar spine. Physical activity caused a site-specific increase in bone density, affecting the legs more than the lumbar spine, but there was no significant difference in the effect of exercise between the healthy weight and the overweight/obese group.

conclusionsThe smaller change in BMAD over the 9 months and lower BMAD per unit lean mass in overweight/obese compared with healthy weight children may indicate a slower rate of bone mass accrual, which may have implications for bone health during skeletal growth in obese/overweight children.

Indexed as

Exercise TherapyBody WeightBone DensityChildHumansLeg BonesLumbar VertebraePediatric Obesity

Identifiers

PMID31479005
PMCPMC6962537

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.