Evidence map›Paper›PMID 31478785›Full record

ArticleSurgical infections2020

Proteomic Pathway Analysis of Monocyte-Derived Exosomes during Surgical Sepsis Identifies Immunoregulatory Functions.

Jon R Wisler, Kanhaiya Singh, Adara R Mccarty, Ahmed Safwat Elsayed Abouhashem, John W Christman, Chandan K Sen

Open access · greenAbstract read
In one paragraph

Article in Surgical infections, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
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  12. Extracellular vesicles participate in the pathogenesis of sepsis.Frontiers in cellular and infection microbiology · 2022
    Review
  13. Article
  14. Review
  15. Extracellular Vesicles: A Double-Edged Sword in Sepsis.Pharmaceuticals (Basel, Switzerland) · 2021
    Review
  16. Article
  17. Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jon R WislerDivison of Trauma and Critical Care, Department of Surgery, Ohio State University, Columbus, Ohio.
Kanhaiya SinghIndiana Center for Regenerative Medicine & Engineering, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana.
Adara R MccartyDivison of Trauma and Critical Care, Department of Surgery, Ohio State University, Columbus, Ohio.
Ahmed Safwat Elsayed AbouhashemIndiana Center for Regenerative Medicine & Engineering, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana.
John W ChristmanDivision of Pulmonary, Critical Care and Sleep, Department of Medicine, Ohio State University, Columbus, Ohio.
Chandan K SenIndiana Center for Regenerative Medicine & Engineering, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana.
Indiana University School of MedicineIndiana University – Purdue University Indianapolis · USThe Ohio State University · US

Funding

REGULATION OF THE MACROPHAGE INFLAMMATORY PHENOTYPE IN ARDSR01HL137224 · NHLBI · OHIO STATE UNIVERSITY · PI CHRISTMAN, JOHN W, KARPURAPU, MANJULA · 2018 to 2025
$4.5M
NHLBI NIH HHS R01 HL137224
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Down-RegulationExosomesHumansImmunosuppression TherapyInflammationLipopolysaccharidesModels, BiologicalMonocytesProteomicsSepsisTumor Necrosis Factor-alphaUp-RegulationLipopolysaccharidesTumor Necrosis Factor-alphaanti-inflammationcompensatory anti-inflammatory response syndrome (CARS)exosomesimmunosuppressionproteomicssepsissystemic inflammatory response syndrome (SIRS)

Identifiers

PMID31478785
PMCPMC7133458
OpenAlexW2972054198

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.