Evidence map›Paper›PMID 31478454›Full record

ArticleCell cycle (Georgetown, Tex.)2019

Myotubularin related protein 7 is essential for the spermatogonial stem cell homeostasis via PI3K/AKT signaling.

Dan Zhao, Cong Shen, Tingting Gao, Hong Li, Yueshuai Guo, Feng Li, Chenchen Liu, Yuanyuan Liu, Xia Chen, Xi Zhang and 10 more

Open access · bronzeAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Comprehensive Analysis of the Transcriptome-Wide mInternational journal of molecular sciences · 2023
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  9. Article
  10. PeerJ · 2023
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  11. Article
  12. Article
  13. Article
  14. Long non-coding RNAThe Journal of international medical research · 2022
    Article
  15. Testis-enrichedTranslational andrology and urology · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. E3 ubiquitin ligase ASB17 is required for spermiation in mice.Translational andrology and urology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 1 country.

Dan ZhaoFourth Affiliated Hospital of Jiangsu University , Zhenjiang , China.
Cong ShenCenter for Reproduction and Genetics, Suzhou Municipal Hospital, the Affiliated Suzhou Hospital of Nanjing Medical University , Suzhou , China.ORCID https://orcid.org/0000-0002-9982-176X
Tingting GaoCenter of Clinical Reproductive Medicine, the Affiliated Changzhou Matemity and Child Health Care Hospital of Nanjing Medical University , Changzhou , China.
Hong LiCenter for Reproduction and Genetics, Suzhou Municipal Hospital, the Affiliated Suzhou Hospital of Nanjing Medical University , Suzhou , China.
Yueshuai GuoState Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University , Nanjing , China.
Feng LiFourth Affiliated Hospital of Jiangsu University , Zhenjiang , China.
Chenchen LiuState Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University , Nanjing , China.
Yuanyuan LiuCenter for Reproduction and Genetics, Suzhou Municipal Hospital, the Affiliated Suzhou Hospital of Nanjing Medical University , Suzhou , China.
Xia ChenDepartment of Obstetrics and Gynecology, Affiliated Hospital of Jiangsu University, Jiangsu University , Zhenjiang , China.
Xi ZhangState Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University , Nanjing , China.
Yangyang WuState Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University , Nanjing , China.
Yi YuCenter for Reproduction and Genetics, Suzhou Municipal Hospital, the Affiliated Suzhou Hospital of Nanjing Medical University , Suzhou , China.
Meng LinState Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University , Nanjing , China.
Yan YuanHuman Reproductive and Genetic center, Affiliated Hospital of Jiangnan University , Wuxi , China.
Xiaofang ChenFourth Affiliated Hospital of Jiangsu University , Zhenjiang , China.
Xiaoyan HuangState Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University , Nanjing , China.
Shenmin YangCenter for Reproduction and Genetics, Suzhou Municipal Hospital, the Affiliated Suzhou Hospital of Nanjing Medical University , Suzhou , China.
Jun YuDepartment of Obstetrics and Gynecology, Affiliated Hospital of Jiangsu University, Jiangsu University , Zhenjiang , China.
Jun ZhangState Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University , Nanjing , China.
Bo ZhengCenter for Reproduction and Genetics, Suzhou Municipal Hospital, the Affiliated Suzhou Hospital of Nanjing Medical University , Suzhou , China.ORCID https://orcid.org/0000-0002-1496-0753
Nanjing Medical University · CNSuzhou Municipal Hospital · CNJiangsu University · CNJiangnan University · CNNanjing Maternity and Child Health Care Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myotubularin related protein 7 (MTMR7), a key member of the MTMR family, depicts phosphatase activity and is involved in myogenesis and tumor growth. We have previously identified MTMR7 in the proteomic profile of mouse spermatogonial stem cell (SSC) maturation and differentiation, implying that MTMR7 is associated with neonatal testicular development. In this study, to further explore the distribution and function of MTMR7 in mouse testis, we studied the effect of

Indexed as

AnimalsApoptosisCell CycleCell ProliferationCells, CulturedChromonesGene Knockdown TechniquesHomeostasisMaleMiceMice, Inbred ICRMorpholinesMorpholinosOrganoidsPhosphatidylinositol 3-KinasesPhosphoinositide-3 Kinase Inhibitors2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneChromonesMorpholinesMorpholinosMtmr7 protein, mousePhosphatidylinositol 3-KinasesPhosphoinositide-3 Kinase InhibitorsProtein Tyrosine Phosphatases, Non-ReceptorProto-Oncogene Proteins c-aktgerm cellsMyotubularin related protein 7 (MTMR7)PI3K/AKT signalingspermatogonial stem cell (SSC)

Identifiers

PMID31478454
PMCPMC6773228
OpenAlexW2972263483

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.