ArticleOrganic letters2019
1,3,4-Oxadiazoles by Ugi-Tetrazole and Huisgen Reaction.
Article in Organic letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- One-Step Construction of 1,3,4-Oxadiazoles with Anticancer Activity from Tertiary Amines via a Sequential Copper(I)-Catalyzed Oxidative Ugi/aza-Wittig Reaction.Molecules (Basel, Switzerland) · 2024Article
- Anti-inflammatory and Antimicrobial Potential of 1, 3, 4-oxadiazoles and its Derivatives: A Review.Current organic synthesis · 2024Review
- Access to Isoquinolin-2(1The Journal of organic chemistry · 2022Article
- Copper-Catalyzed One-Pot Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles from Arylacetic Acids and HydrazidesACS omega · 2022Article
- General α-Amino 1,3,4-Oxadiazole Synthesis via Late-Stage Reductive Functionalization of Tertiary Amides and Lactams*.Angewandte Chemie (International ed. in English) · 2021Article
- Isoquinolone-4-Carboxylic Acids by Ammonia-Ugi-4CR and Copper-Catalyzed Domino Reaction.The Journal of organic chemistry · 2021Article
- An efficient synthesis tetrazole and oxadiazole analogues of novel 2'-deoxy-C-nucleosides and their antitumor activity.Bioorganic & medicinal chemistry letters · 2020Article
- Copper-Catalyzed Modular Assembly of Polyheterocycles.The Journal of organic chemistry · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Easy to perform, functional group tolerant, and short syntheses of the privileged scaffold oxadiazole are highly desired. Here, a metal-free protocol for MCR-based synthesis of 2,5-disubstituted 1,3,4-oxadiazoles via a Ugi-tetrazole/Huisgen sequence was developed. Optimization and scope and limitations of this short and general sequence are described. The reaction was also successfully performed on a gram scale.
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Registered trials
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