Evidence map›Paper›PMID 31478207›Full record

ArticleMuscle & nerve2019

Employment in refractory myasthenia gravis: A Myasthenia Gravis Foundation of America Registry analysis.

Linda Harris, Inmaculada B Aban, Haichang Xin, Gary Cutter

Open access · hybridAbstract read
In one paragraph

Article in Muscle & nerve, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Linda HarrisFormerly of Alexion Pharmaceuticals, Inc., Boston, Massachusetts.
Inmaculada B AbanDepartment of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama.
Haichang XinFormerly of the Department of Health Care Organization and Policy, University of Alabama at Birmingham, Birmingham, Alabama.
Gary CutterDepartment of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama.
University of Alabama at Birmingham · USAlexion Pharmaceuticals (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLabor-market participation is potentially very difficult for patients with refractory myasthenia gravis (MG). In this study, employment status and work absences are compared between refractory and nonrefractory MG.

methodsAdults (aged 18-64 years, all diagnosed ≥2 years previously) were included if enrolled in the Myasthenia Gravis Foundation of America Patient Registry during July 2013 to February 2018.

resultsSeventy-six patients (9.2%) had refractory and 749 (90.8%) had nonrefractory disease; demographic data did not differ between groups. Relative to the nonrefractory group, the refractory group patients were more than twice as likely to work fewer hours per week (odds ratio [95% confidence interval]: currently employed, 2.777 [1.640-4.704]; employed over previous 6 months, 2.643 [1.595-4.380]), but those employed were not more likely to be absent from work. DISCUSSION: Because absence from the labor market adversely affects quality of life and personal finances, these findings reaffirm the considerable disease burden associated with refractory MG.

Indexed as

AdolescentAdultEmploymentFemaleHumansMaleMiddle AgedMyasthenia GravisSick LeaveTreatment FailureUnemploymentYoung Adultabsence from workemploymentMGFA Registrymyasthenia gravispatient surveyrefractory disease

Identifiers

PMID31478207
PMCPMC6900169
OpenAlexW2972066878

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.