Evidence map›Paper›PMID 31478164›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2020

Sleep, quality of life, and depression in endometrial cancer survivors with obesity seeking weight loss.

Nora L Nock, Anastasia Dimitropoulos, Kristine M Zanotti, Steven Waggoner, Christa Nagel, Mladen Golubic, Chad M Michener, John P Kirwan, Jay Alberts

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01870947 (REWARD), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01870947 nacompletednot on this map

REWARD (Revving-Up Exercise for Sustained Weight Loss by Altering Neurological Reward and Drive): A Randomized Trial of Assisted Exercise in Obese Endometrial Cancer Patients

TypeinterventionalSponsorCase Comprehensive Cancer CenterRan2011 to 2019Enrolled95ConditionsStage I Endometrial Adenocarcinoma, Uterine Cancer, ObesityArmsExercise on stationary recumbent exercise cycle, Health Education, Questionnaires, Neuroimaging, Genetic and Biomarkers
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Sleep deprivation and quality of life among uterine cancer survivors: systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it
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  13. Sleep and gynecological cancer outcomes: opportunities to improve quality of life and survival.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2022
    Review
  14. Article
  15. Is sleep associated with BMI, waist circumference, and diet among long-term colorectal cancer survivors? Results from the population-based PROFILES registry.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Nora L NockDepartment of Population and Quantitative Health Sciences, Case Western Reserve University, Wolstein Research Building, 2103 Cornell Road, Cleveland, OH, 44106, USA. nln@case.edu.ORCID http://orcid.org/0000-0002-6476-6692
Anastasia DimitropoulosDepartment of Psychological Sciences, Case Western Reserve University, Cleveland, OH, USA.
Kristine M ZanottiDepartment of Reproductive Biology, Case Western Reserve University, Cleveland, OH, USA.
Steven WaggonerDepartment of Reproductive Biology, Case Western Reserve University, Cleveland, OH, USA.
Christa NagelDepartment of Reproductive Biology, Case Western Reserve University, Cleveland, OH, USA.
Mladen GolubicCenter for Lifestyle Medicine, Wellness and Preventive Medicine, Cleveland Clinic, Cleveland, OH, USA.
Chad M MichenerDepartment of Obstetrics and Gynecology, Cleveland Clinic, Cleveland, OH, USA.
John P KirwanDepartment of Pathobiology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Jay AlbertsDepartment of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
University Hospitals Cleveland Medical Center · USCleveland Clinic · USCleveland Clinic Lerner College of Medicine · USCase Western Reserve University · USCornell University · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024989 · NCRR · CASE WESTERN RESERVE UNIVERSITY · PI DAVIS, PAMELA B · 2007 to 2011
$53.7M
Clinical and Translational Science Collaborative of ClevelandUL1TR002548 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI MCCOMSEY, GRACE A · 2018 to 2022
$35.5M
Revving-Up Exercise for Sustained Weight-Loss by Altering Neurological Reward & DR01CA175100 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI NOCK, NORA L. · 2013 to 2017
$2.5M
National Cancer Institute (US) R01-CA175100NCATS NIH HHS UL1 TR002548NCI NIH HHS R01 CA175100NCRR NIH HHS UL1 RR024989
6 · The paper itself

Abstract

purposeIncidence and mortality rates of uterine cancer are increasing and, obesity, which is also rising, has been associated with uterine cancer development and mortality. A recent study found that poor sleep quality is common among endometrial cancer survivors and those with obesity had more sleep disturbances than those having normal weight. However, it is unclear if higher levels of obesity (Class III, BMI ≥ 40 kg/m

methodsWe evaluated sleep, depression, and quality of life in 100 Stage I endometrial cancer survivors with obesity seeking weight loss enrolled in a lifestyle intervention (NCT01870947) at baseline.

resultsThe average age was 60 years and mean BMI was 42.1 kg/m

conclusionsOur results reveal that endometrial cancer survivors with class III compared with class I obesity have poorer sleep quality, higher depression, and lower quality of life. Given the rising rates of obesity and uterine cancer mortality, interventions to combat both obesity and poor sleep are needed.

Indexed as

Body Mass IndexCancer SurvivorsDepressionEndometrial NeoplasmsFemaleHumansLife StyleMiddle AgedNeoplasm StagingObesityQuality of LifeSleepSleep Initiation and Maintenance DisordersWeight LossWeight Reduction ProgramsEndometrial cancer survivorsObesityQuality of lifeSleep

Identifiers

PMID31478164
PMCPMC7050326
OpenAlexW2970686826

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.