ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2019
Elderly males with or without existing osteoporotic vertebral fracture have much lower future vertebral fracture risk than elderly females: the MrOS (Hong Kong) year-4 follow-up spine radiograph study.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed.
- A higher threshold of lumbar spine QCT trabecular BMD of < 95 or < 100 mg/mL for fragility fracture risk screening among Caucasian men than that of < 80 mg/mL for Caucasian women.Skeletal radiology · 2026Article
- Lumbar spine DXA T-score and QCT BMD cutpoint values for defining osteofrailia among older men: a framework for further refinement.Skeletal radiology · 2026Review
- Relevance of vertebral fractural deformity for hip fracture prediction: a community-based study of older Chinese women and men.Skeletal radiology · 2026Article
- Trends in prevalence of spine fractures and risk factors in spine fractures among US adults, 1999-2018.Scientific reports · 2025Article
- Majority of hip fragility fractures among older people can be predicted by a DXA examination: an updated analysis of literature results and empirical Chinese data with a focus on the validation of the newly proposed osteofrailia criterion for men.Quantitative imaging in medicine and surgery · 2025Article
- Weak correlation between osteoporotic-like vertebral fracture severity and densitometric T-scores in older Chinese men.Annals of translational medicine · 2023Article
- Conversion of osteoporotic-like vertebral fracture severity score to osteoporosis T-score equivalent status: A framework study for older Chinese men.Osteoporosis and sarcopenia · 2023Article
- Osteoporotic-like vertebral fracture with less than 20% height loss is associated with increased further vertebral fracture risk in older women: the MrOS and MsOS (Hong Kong) year-18 follow-up radiograph results.Quantitative imaging in medicine and surgery · 2023Article
- 'Healthier Chinese spine': an update of osteoporotic fractures in men (MrOS) and in women (MsOS) Hong Kong spine radiograph studies.Quantitative imaging in medicine and surgery · 2022Review
- Fragility fracture prevalence among elderly Chinese is no more than half of that of elderly Caucasians.Quantitative imaging in medicine and surgery · 2022Article
- Radiographic osteoporotic vertebral fractures in elderly men: a brief review focusing on differences between the sexes.Quantitative imaging in medicine and surgery · 2020Review
- Diagnosis and grading of radiographic osteoporotic vertebral deformity by general radiologists after a brief self-learning period.Journal of thoracic disease · 2020Article
- Existing severe osteoporotic vertebral fractures in elderly Chinese males were only weakly associated with higher further vertebral fracture risk at year-4 follow-up.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020Article
- Underreporting characteristics of osteoporotic vertebral fracture in back pain clinic patients of a tertiary hospital in China.Journal of orthopaedic translation · 2020Article
- Gender and the recognition of vertebral fractures.Quantitative imaging in medicine and surgery · 2020Article
- Semi-quantitative grading and extended semi-quantitative grading for osteoporotic vertebral deformity: a radiographic image database for education and calibration.Annals of translational medicine · 2020Review
- On the possibility of over-diagnosis of osteoporotic vertebral fracture at mid-thoracic level.Journal of thoracic disease · 2019Article
- Corrigendum to how to define an osteoporotic vertebral fracture.Quantitative imaging in medicine and surgery · 2019Article
- How to define an osteoporotic vertebral fracture?Quantitative imaging in medicine and surgery · 2019Article
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Abstract
MrOS (Hong Kong)'s year-4 follow-up shows, for subjects at baseline without vertebral deformity (VD) and endplate or/and cortex fracture (ECF), the VD progression/new VD rate during follow-up in males was half of our paired MsOS (Hong Kong) study's results. For those with VD or ECF, the VD progression/new VD was less than one sixth of females' rate.
introductionThis study documents MrOS (Hong Kong)'s year-4 follow-up, and the results are compared with the MsOS (Hong Kong) study. Of elderly females with Genant's grade-0, -1, -2, and -3 VD, at year-4 follow-up, 4.6%, 8%, 10.6%, and 28.9% had at least one VD progression or incident VD, respectively.
methodsSpine radiographs of 1500 Chinese males with baseline (mean age 71.7 years, range 65-91 years) and year-4 follow-up were evaluated according to Genant's VD criteria and ECF (non-existent, ECF0; or existent, ECF1). Grade-2 VDs were divided into mild (VD2m, 25-34% height loss) and severe (VD2s, 34-40% height loss) subgroups. Study subjects were graded into eight categories: VD0/ECF0, VD1/ECF0, VD2m/ECF0, VD0/ECF1, VD1/ECF1, VD2m/ECF1, VD2s/ECF1, and VD3/ECF1. With an existing VD, a further height loss of ≥ 15% was a VD progression. A new VD incident was a change from grade-0 to grade-2/3, or to grade-1 with ≥ 10% height loss.
resultsOf subjects with Genant's grade-0, 2.05% (25/1219) developed at least one VD progression or/and new VD, while of subjects with Genant's grade-1, -2, and -3 VD, only 2% (3/149), 3.1% (3/96), and 2.8% (1/36) developed at least one VD progression/new VD, respectively. Among the three ECF0 groups, there was a significant difference in new ECF incidence, with VD0/ECF0 being the lowest and VD2m/ECF0 being the highest.
conclusionVD progression/new VD is much less common in elderly men than in elderly women. Vertebrae with VD had a higher risk of developing ECF.
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