Evidence map›Paper›PMID 31478011›Full record

ArticleLupus science & medicine2019

Jaccoud's arthropathy in SLE: findings from a Latin American multiethnic population.

Rosana Quintana, Guillermo Pons-Estel, Karen Roberts, Monica Sacnún, Guillermo Berbotto, Mercedes A Garcia, Veronica Saurit, Leonor Barile-Fabris, Eduardo M Acevedo-Vazquez, João C Tavares Brenol and 5 more

Open access · goldAbstract read
In one paragraph

Article in Lupus science & medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 6 countries.

Rosana QuintanaDepartment of Internal Medicine, Centro Regional de Enfermedades Autoinmunes y Reumáticas (CREAR), Rosario, Argentina.ORCID 0000-0003-0643-2755
Guillermo Pons-EstelDepartment of Internal Medicine, Centro Regional de Enfermedades Autoinmunes y Reumáticas (CREAR), Rosario, Argentina.ORCID 0000-0002-0647-929X
Karen RobertsDepartment of Rheumatology, Hospital Provincial de Rosario, Rosario, Argentina.
Monica SacnúnDepartment of Rheumatology, Hospital Provincial de Rosario, Rosario, Argentina.
Guillermo BerbottoDepartment of Rheumatology, Hospital Escuela Eva Perón, Granadero Baigorria, Argentina.
Mercedes A GarciaDepartment of Rheumatology, Hospital Interzonal General de Agudos General San Martín, La Plata, Argentina.
Veronica SauritDepartment of Rheumatology, Hospital Privado, Cordoba, Cordoba, Argentina.
Leonor Barile-FabrisDepartment of Rheumatology, Hospital Angeles del Pedregal, Ciudad de México, Ciudad de Mexico, Mexico.
Eduardo M Acevedo-VazquezDepartment of Rheumatology, Hospital Nacional Guillermo Almenara Irigoyen, ESSALUD, Lima, Peru.
João C Tavares BrenolDepartment of Rheumatology, Hospital das Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Emilia I SatoDepartment of Rheumatology, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
Antonio IglesiasDepartment of Medicine, Universidad Nacional de Colombia, Bogota, Colombia.
Oscar UribeDepartment of Rheumatology, Universidad de Antioquia, Hospital Universitario "Fundación San Vicente", Medellin, Colombia.
Graciela AlarconDepartment of Medicine, Division of Clinical Immunology and Rheumatology, School of Medicine, The University of Alabama at Birmingham, Birmingham, England, USA.
Bernardo A Pons-EstelDepartment of Internal Medicine, Centro Regional de Enfermedades Autoinmunes y Reumáticas (CREAR), Rosario, Argentina.
Hospital Provincial de Rosario · ARHospital Angeles Pedregal · MXHospital Base Guillermo Almenara Irigoyen · PEHospital Privado · ARHospital Universitario de San Vicente Fundación · CONational University of General San Martín · ARUniversidade Federal de São Paulo · BRUniversidade Federal do Rio Grande do Sul · BRUniversidad Nacional de Colombia · COUniversidad Peruana Cayetano Heredia · PE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the clinical, laboratory and outcome features of SLE patients with and without Jaccoud's arthropathy (JA) from the

methods1480 patients with SLE [(34 centres, 9 Latin American countries with a recent diagnosis (≤2 years)] constitute the GLADEL cohort. JA was defined as reducible deformity of the metacarpophalangeal axis, without radiographic erosions at any time. Within this cohort, a nested case-control study was carried out. Control was matched for age, gender and centre in a 1:3 proportion. The variables included were: sociodemographic, clinical and immunological features, disease activity, damage and mortality. Comparisons were performed with Wilcoxon and χ

resultsOf 1480 patients, 17 (1.1%) JA patients were identified; 16 (94.1%) of them were women, mean age: 31.0 years (SD 12.0). Five (29.4%) patients presented JA at SLE diagnosis and 12 (70.6%) after. The median follow-up time and all disease features were comparable in both groups except for a higher frequency of pneumonitis in the patients with JA [4 (23.5) vs 1 (2.0); p=0.012; (OR: 15.4; 95% CI 1.6 to 149.6)]. The SLE disease activity index, Systemic Lupus International Collaborating Clinics/American College of Rheumatology damage Index and the Kaplan-Meier survival curve were similar in both groups.

conclusionJA may tend to appear early in the course of SLE; it seems not to have an impact on disease activity, damage accrual or in survival.

Indexed as

deforming arthropathydisease activityJaccoud’s arthropathymortalitySystemic lupus erythematosus

Identifiers

PMID31478011
PMCPMC6703282
OpenAlexW2968507135

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.