ReviewNature neuroscience2019
The next generation of approaches to investigate the link between synaptic plasticity and learning.
Review in Nature neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review and meta-analysis of the effects of exercise on cognitive impairment and neuroprotective mechanisms in diabetes mellitus animal models.Metabolic brain disease · 2024Pooled it
- A Single OLED With Hybrid Synaptic Plasticity Enabling In Situ Neuromorphic Processing and Visualization.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- mGluR5 in ECAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Esketamine Alleviates Postoperative Cognitive Dysfunction via Rock2/Add1 Signaling Pathway in Aged Mice.Neurochemical research · 2026Article
- Altered Structural Plasticity Mediated by mGlu and NMDA Receptors and Impaired Cognition in a Genetic ASD Model (Shank3The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Microglial PGC-1α alleviates synaptic damage and cognitive impairments following anesthesia and surgery by suppressing excessive synaptic pruning in aged mice.International journal of biological sciences · 2026Article
- Early changes in the properties of CA3 engram cells explored with a novel viral tool in mice.eLife · 2025Article
- The Cooperation of Neurogranin with Calmodulin Promotes the Treatment of Aging-Related Diseases via Regular Exercise.Molecular neurobiology · 2025Review
- Thin-Film Silicon Nanosheet-Based Neuromorphic Assemblies.ACS applied materials & interfaces · 2025Article
- All-optical voltage interrogation for probing synaptic plasticity in vivo.Nature communications · 2025Article
- Dynamic mapping of network-level LTP in the hippocampus via high-resolution bioelectrical sensing.APL bioengineering · 2025Article
- Article
- The X-linked intellectual disability gene CUL4B is critical for memory and synaptic function.Acta neuropathologica communications · 2024Article
- Single-dose methamphetamine administration impairs ORM retrieval in mice via excessive DA-mediated inhibition of PrLActa pharmacologica Sinica · 2024Article
- Morphological correlates of synaptic protein turnover in the mouse brain.Life science alliance · 2024Article
- FLUID: a fluorescence-friendly lipid-compatible ultrafast clearing method.Biomedical optics express · 2024Article
- Article
- Modeling biological memory network by an autonomous and adaptive multi-agent system.Brain informatics · 2024Article
- Haploinsufficiency of GABAThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Chromophore-assisted light inactivation of target proteins for singularity biology.Biophysics and physicobiology · 2024Review
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Activity-dependent synaptic plasticity has since long been proposed to represent the subcellular substrate of learning and memory, one of the most important behavioral processes through which we adapt to our environment. Despite the undisputed importance of synaptic plasticity for brain function, its exact contribution to learning processes in the context of cellular and connectivity modifications remains obscure. Causally bridging synaptic and behavioral modifications indeed remains limited by the available tools to measure and control synaptic strength and plasticity in vivo under behaviorally relevant conditions. After a brief summary of the current state of knowledge of the links between synaptic plasticity and learning, we will review and discuss the available and desired tools to progress in this endeavor.
Indexed as
Identifiers
31477899What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.