Evidence map›Paper›PMID 31477823›Full record

ArticleJournal of human hypertension2020

The association of stage 1 hypertension defined by the 2017 ACC/AHA hypertension guideline and subsequent cardiovascular events among adults <50 years.

Sitong Liu, Yali Wang, Yanxia Xie, Jia Zheng, Rongrong Guo, Yue Dai, Zhaoqing Sun, Liying Xing, Xingang Zhang, Yingxian Sun and 1 more

Erratum issuedAbstract read
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In one paragraph

Article in Journal of human hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Sitong Liu *Department of Clinical Epidemiology, Library, Shengjing Hospital of China Medical University, 110004, Shenyang, People's Republic of China.
Yali Wang *Department of Clinical Epidemiology, Library, Shengjing Hospital of China Medical University, 110004, Shenyang, People's Republic of China.
Yanxia XieDepartment of Clinical Epidemiology, Library, Shengjing Hospital of China Medical University, 110004, Shenyang, People's Republic of China.
Jia ZhengDepartment of Clinical Epidemiology, Library, Shengjing Hospital of China Medical University, 110004, Shenyang, People's Republic of China.
Rongrong GuoDepartment of Clinical Epidemiology, Library, Shengjing Hospital of China Medical University, 110004, Shenyang, People's Republic of China.
Yue DaiDepartment of Clinical Epidemiology, Library, Shengjing Hospital of China Medical University, 110004, Shenyang, People's Republic of China.
Zhaoqing SunDepartment of Cardiology, Shengjing Hospital of China Medical University, 110004, Shenyang, People's Republic of China.
Liying XingInstitute of Chronic Disease, Liaoning Provincial Center for Disease Control and Prevention, 110005, Shenyang, People's Republic of China.
Xingang ZhangDepartment of Cardiology, The First Affiliated Hospital of China Medical University, 110001, Shenyang, People's Republic of China.
Yingxian SunDepartment of Cardiology, Shengjing Hospital of China Medical University, 110004, Shenyang, People's Republic of China. sunyingxian12@126.com.
Liqiang ZhengDepartment of Clinical Epidemiology, Library, Shengjing Hospital of China Medical University, 110004, Shenyang, People's Republic of China. liqiangzheng@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was performed to investigate the association between stage 1 hypertension defined by the 2017 ACC/AHA guidelines and the risk of adverse events among adults aged 35 to 49 years. A total of 20,072 adults aged 35-49 years, without a history of cardiovascular disease (CVD) at baseline were included in the present study. Adjusted Cox proportional hazards models were applied to estimate hazard ratios (HRs) with 95% confidence intervals (CIs). During a median follow-up period of 12.5 years, the results indicated that 777 subjects suffered all-cause death and 299 subjects developed CVD. A total of 830 subjects were involved in incident stroke and 141 subjects had a myocardial infarction (MI). Stage 1 hypertension had a HR (95% CI) of 1.38 (1.13-1.70) for all-cause mortality, 1.74 (1.20-2.53) for CVD mortality, 1.78 for (1.40-2.26) for stroke incidence, and 1.64 (0.99-2.71) for MI incidence, respectively, compared with blood pressure (BP) <120/<80 mmHg. The results show that after adjusting for sex, age, and other potential CVD factors, the incidence of stroke was the only parameter significantly associated with stage 1 hypertension (HR and 95% CI: 1.53, 1.20-1.95). Stage 1 hypertension defined by the 2017 ACC/AHA guidelines was associated with an increased risk of stroke among adults aged 35 to 49 years in rural areas of China.

Indexed as

Cardiovascular DiseasesHypertensionMyocardial InfarctionStrokeAdultBlood PressureHumansIncidenceRisk Factors

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.