Evidence map›Paper›PMID 31477778›Full record

ArticleScientific reports2019

VIVA (VIsualization of VAriants): A VCF File Visualization Tool.

G A Tollefson, J Schuster, F Gelin, A Agudelo, A Ragavendran, I Restrepo, P Stey, J Padbury, A Uzun

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

G A TollefsonDepartment of Pediatrics, Women and Infants Hospital of RI, Providence, RI, USA.
J SchusterDepartment of Pediatrics, Women and Infants Hospital of RI, Providence, RI, USA.
F GelinData Science Practice, Brown University, Providence, RI, USA.
A AgudeloDepartment of Pediatrics, Women and Infants Hospital of RI, Providence, RI, USA.
A RagavendranData Science Practice, Brown University, Providence, RI, USA.
I RestrepoData Science Practice, Brown University, Providence, RI, USA.
P SteyData Science Practice, Brown University, Providence, RI, USA.
J PadburyDepartment of Pediatrics, Women and Infants Hospital of RI, Providence, RI, USA.
A UzunDepartment of Pediatrics, Women and Infants Hospital of RI, Providence, RI, USA. alper_uzun@brown.edu.ORCID http://orcid.org/0000-0001-6489-8591

Funding

The role of Sirtuins in neurodegenerative diseaseP20GM109035 · NIGMS · BROWN UNIVERSITY · PI WONG, IAN Y · 2016 to 2025
$22.6M
Transcriptional Profiling of Exosomes Defines Molecular Phenotype of PreclampsiaP20GM121298 · NIGMS · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI SHARMA, SURENDRA · 2017 to 2021
$12.6M
Research CoreP30GM114750 · NIGMS · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI SHAW, SUNIL K · 2015 to 2019
$4.5M
NIGMS NIH HHS P20 GM109035NIGMS NIH HHS P20 GM121298NIGMS NIH HHS P30 GM114750
6 · The paper itself

Abstract

High-throughput sequencing produces an extraordinary amount of genomic data that is organized into a number of high-dimension datasets. Accordingly, visualization of genomic data has become essential for quality control, exploration, and data interpretation. The Variant Call Format (VCF) is a text file format generated during the variant calling process that contains genomic information and locations of variants in a group of sequenced samples. The current workflow for visualization of genomic variant data from VCF files requires use of a combination of existing tools. Here, we describe VIVA (VIsualization of VAriants), a command line utility and Jupyter Notebook based tool for evaluating and sharing genomic data for variant analysis and quality control of sequencing experiments from VCF files. VIVA combines the functionality of existing tools into a single command to interactively evaluate and share genomic data, as well as create publication quality graphics.

Indexed as

Genetic VariationSoftwareHumansTime FactorsWorkflow

Identifiers

PMID31477778
PMCPMC6718772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.